Imatinib radiosensitizes bladder cancer by targeting homologous recombination.
Radiotherapy is a major treatment modality used to treat muscle-invasive bladder cancer, with patient outcomes similar to surgery. However, radioresistance is a significant factor in treatment failure. Cell-free extracts of muscle-invasive bladder tumors are defective in nonhomologous end-joining (N...
Автори: | Qiao, B, Kerr, M, Groselj, B, Teo, M, Knowles, M, Bristow, R, Phillips, R, Kiltie, A |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2013
|
Схожі ресурси
Схожі ресурси
-
Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity.
за авторством: Choudhury, A, та інші
Опубліковано: (2009) -
E3 ligase cIAP2 mediates downregulation of MRE11 and radiosensitization in response to HDAC inhibition in bladder cancer
за авторством: Nicholson, J, та інші
Опубліковано: (2017) -
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination
за авторством: Nina M. S. Gustafsson, та інші
Опубліковано: (2018-09-01) -
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
за авторством: Groselj, B, та інші
Опубліковано: (2013) -
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
за авторством: Groselj, B, та інші
Опубліковано: (2013)