Development of a simple in vitro assay to assess digestion of the extracellular matrix of the human pancreas by collagenase enzyme blends

Despite huge advances in the field of islet transplantation over the last two decades, current islet isolation methods remain suboptimal, with transplantable yields obtained in less than half of all pancreases processed worldwide. Successful islet isolation is dependent on the ability of collagenase...

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Bibliographic Details
Main Authors: Spiers, RM, Cross, SE, Brown, HL, Bateman, PA, Hughes, SJ, Johnson, PRV
Format: Journal article
Published: SAGE Publications 2018