Glucosylceramide modulates membrane traffic along the endocytic pathway.

Glycosphingolipids are endocytosed and targeted to the Golgi apparatus, but are mistargeted to lysosomes in numerous sphingolipidoses. Substrate reduction therapy utilizes imino sugars to inhibit glucosylceramide synthase and potentially abrogate the effects of storage. Gaucher disease is a heredita...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Sillence, D, Puri, V, Marks, D, Butters, T, Dwek, R, Pagano, R, Platt, F
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2002

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