Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin

Objective: A major site of action for the atheroprotective drug nicotinic acid (NA) is adipose tissue, via the G-protein-coupled receptor, GPR109A. Since, adipose tissue is an active secretory organ that contributes both positively and negatively to systemic inflammatory processes associated with ca...

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Hlavní autoři: Digby, J, McNeill, E, Dyar, O, Lam, V, Greaves, DR, Choudhury, R
Médium: Journal article
Jazyk:English
Vydáno: 2010