Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.

Lignende værker

• Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.
  af: Degrève, B, et al.
  Udgivet: (2000)
• Characterization of multiple nuclear localization signals in herpes simplex virus type 1 thymidine kinase.
  af: Degrève, B, et al.
  Udgivet: (1999)
• The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
  af: Balzarini, J, et al.
  Udgivet: (2002)
• Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase.
  af: Balzarini, J, et al.
  Udgivet: (2003)
• Crystal structure of varicella zoster virus thymidine kinase.
  af: Bird, L, et al.
  Udgivet: (2003)