Dihydrogen‐driven NADPH recycling in imine reduction and P450‐catalyzed oxidations mediated by an engineered O2‐tolerant hydrogenase

Dihydrogen‐driven NADPH recycling in imine reduction and P450‐catalyzed oxidations mediated by an engineered O2‐tolerant hydrogenase

The O2‐tolerant NAD+‐reducing hydrogenase (SH) from Ralstonia eutropha (Cupriavidus necator) has already been applied in vitro and in vivo for H2‐driven NADH recycling in coupled enzymatic reactions with various NADH‐dependent oxidoreductases. To expand the scope for application in NADPH‐dependent b...

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Bibliographische Detailangaben
Hauptverfasser:	Preissler, J, Reeve, HA, Zhu, T, Nicholson, J, Urata, K, Lauterbach, L, Wong, LL, Vincent, KA, Lenz, O
Format:	Journal article
Sprache:	English
Veröffentlicht:	Wiley 2020

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