Heregulin-induced epigenetic regulation of the utrophin-A promoter.

Utrophin is the autosomal homolog of dystrophin, the product of the Duchenne's muscular dystrophy (DMD) locus. Utrophin is of therapeutic interest since its over-expression can compensate dystrophin's absence. Utrophin is enriched at neuromuscular junctions due to heregulin-mediated utroph...

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Détails bibliographiques
Auteurs principaux: Basu, U, Gyrd-Hansen, M, Baby, S, Lozynska, O, Krag, T, Jensen, C, Frödin, M, Khurana, T
Format: Journal article
Langue:English
Publié: 2007