Cavity-enhanced optical methods for online microfluidic analysis
Absorption spectroscopy is potentially an attractive detection technique for microfluidic applications, as it is universal, label-free, and rapid. However, the short optical pathlength through a microfluidic channel often imposes unacceptable limits on the detection sensitivity. We review a variety...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
2012
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| _version_ | 1826306904699174912 |
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| author | Rushworth, C Davies, J Cabral, J Dolan, P Smith, J Vallance, C |
| author_facet | Rushworth, C Davies, J Cabral, J Dolan, P Smith, J Vallance, C |
| author_sort | Rushworth, C |
| collection | OXFORD |
| description | Absorption spectroscopy is potentially an attractive detection technique for microfluidic applications, as it is universal, label-free, and rapid. However, the short optical pathlength through a microfluidic channel often imposes unacceptable limits on the detection sensitivity. We review a variety of strategies for increasing the pathlength and thereby improving the detection sensitivity of absorption measurements, covering extended-pathlength single-pass methods, multi-pass measurements, and finally a range of cavity-enhanced methods. We conclude that cavity-enhanced approaches show considerable promise for applications in which a high detection sensitivity is required within a small probed volume. © 2012 Elsevier B.V. All rights reserved. |
| first_indexed | 2024-03-07T06:54:58Z |
| format | Journal article |
| id | oxford-uuid:fdd2aada-a087-4c0c-bb56-5e53c4b552e6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:54:58Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:fdd2aada-a087-4c0c-bb56-5e53c4b552e62022-03-27T13:31:44ZCavity-enhanced optical methods for online microfluidic analysisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fdd2aada-a087-4c0c-bb56-5e53c4b552e6EnglishSymplectic Elements at Oxford2012Rushworth, CDavies, JCabral, JDolan, PSmith, JVallance, CAbsorption spectroscopy is potentially an attractive detection technique for microfluidic applications, as it is universal, label-free, and rapid. However, the short optical pathlength through a microfluidic channel often imposes unacceptable limits on the detection sensitivity. We review a variety of strategies for increasing the pathlength and thereby improving the detection sensitivity of absorption measurements, covering extended-pathlength single-pass methods, multi-pass measurements, and finally a range of cavity-enhanced methods. We conclude that cavity-enhanced approaches show considerable promise for applications in which a high detection sensitivity is required within a small probed volume. © 2012 Elsevier B.V. All rights reserved. |
| spellingShingle | Rushworth, C Davies, J Cabral, J Dolan, P Smith, J Vallance, C Cavity-enhanced optical methods for online microfluidic analysis |
| title | Cavity-enhanced optical methods for online microfluidic analysis |
| title_full | Cavity-enhanced optical methods for online microfluidic analysis |
| title_fullStr | Cavity-enhanced optical methods for online microfluidic analysis |
| title_full_unstemmed | Cavity-enhanced optical methods for online microfluidic analysis |
| title_short | Cavity-enhanced optical methods for online microfluidic analysis |
| title_sort | cavity enhanced optical methods for online microfluidic analysis |
| work_keys_str_mv | AT rushworthc cavityenhancedopticalmethodsforonlinemicrofluidicanalysis AT daviesj cavityenhancedopticalmethodsforonlinemicrofluidicanalysis AT cabralj cavityenhancedopticalmethodsforonlinemicrofluidicanalysis AT dolanp cavityenhancedopticalmethodsforonlinemicrofluidicanalysis AT smithj cavityenhancedopticalmethodsforonlinemicrofluidicanalysis AT vallancec cavityenhancedopticalmethodsforonlinemicrofluidicanalysis |