Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia.

Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia.

Somatic genetic abnormalities are initiators and drivers of disease and have proven clinical utility at initial diagnosis. However, the genetic landscape and its clinical utility at relapse is less well understood and has not been studied comprehensively. We analysed cytogenetic data from 427 childr...

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Main Authors: Irving, J, Enshaei, A, Parker, C, Sutton, R, Kuiper, R, Erhorn, A, Minto, L, Venn, N, Law, T, Yu, J, Schwab, C, Davies, R, Matheson, E, Davies, A, Sonneveld, E, Boer, M, Love, S, Harrison, C, Hoogerbrugge, P, Revesz, T, Saha, V, Moorman, A
格式: Journal article
语言:English
出版: American Society of Hematology 2016

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