Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia.

Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia.

Somatic genetic abnormalities are initiators and drivers of disease and have proven clinical utility at initial diagnosis. However, the genetic landscape and its clinical utility at relapse is less well understood and has not been studied comprehensively. We analysed cytogenetic data from 427 childr...

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Bibliografski detalji
Glavni autori: Irving, J, Enshaei, A, Parker, C, Sutton, R, Kuiper, R, Erhorn, A, Minto, L, Venn, N, Law, T, Yu, J, Schwab, C, Davies, R, Matheson, E, Davies, A, Sonneveld, E, Boer, M, Love, S, Harrison, C, Hoogerbrugge, P, Revesz, T, Saha, V, Moorman, A
Format: Journal article
Jezik:English
Izdano: American Society of Hematology 2016

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