Analysis of T cell clones in rheumatoid arthritis.
While it is apparent that much more needs to be learnt about T cells in RA, it seems evident that because of their central role in the immunoregulation their study will provide a lot of valuable information concerning the pathogenesis and perhaps even the aetiology of RA. Two areas of particular imp...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
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Springer-Verlag
1988
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| _version_ | 1797105976660197376 |
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| author | Feldmann, M Londei, M Leech, Z Brennan, F Savill, C Maini, R |
| author_facet | Feldmann, M Londei, M Leech, Z Brennan, F Savill, C Maini, R |
| author_sort | Feldmann, M |
| collection | OXFORD |
| description | While it is apparent that much more needs to be learnt about T cells in RA, it seems evident that because of their central role in the immunoregulation their study will provide a lot of valuable information concerning the pathogenesis and perhaps even the aetiology of RA. Two areas of particular importance are the investigation of epitopes recognised on autoreactive T cells, e. g., on collagen type 11, but also on other T cells, and those expressing the γσ receptor. Knowing which cells are regulating the production of mediators in the RA joint and which mediators are of fundamental importance in perpetuation of the disease process may permit the development of new therapeutic strategies. © 1988 Springer-Verlag. |
| first_indexed | 2024-03-07T06:55:06Z |
| format | Journal article |
| id | oxford-uuid:fde260cd-6718-4fac-ac8d-4fc620d3a43c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:55:06Z |
| publishDate | 1988 |
| publisher | Springer-Verlag |
| record_format | dspace |
| spelling | oxford-uuid:fde260cd-6718-4fac-ac8d-4fc620d3a43c2022-03-27T13:32:02ZAnalysis of T cell clones in rheumatoid arthritis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fde260cd-6718-4fac-ac8d-4fc620d3a43cEnglishSymplectic Elements at OxfordSpringer-Verlag1988Feldmann, MLondei, MLeech, ZBrennan, FSavill, CMaini, RWhile it is apparent that much more needs to be learnt about T cells in RA, it seems evident that because of their central role in the immunoregulation their study will provide a lot of valuable information concerning the pathogenesis and perhaps even the aetiology of RA. Two areas of particular importance are the investigation of epitopes recognised on autoreactive T cells, e. g., on collagen type 11, but also on other T cells, and those expressing the γσ receptor. Knowing which cells are regulating the production of mediators in the RA joint and which mediators are of fundamental importance in perpetuation of the disease process may permit the development of new therapeutic strategies. © 1988 Springer-Verlag. |
| spellingShingle | Feldmann, M Londei, M Leech, Z Brennan, F Savill, C Maini, R Analysis of T cell clones in rheumatoid arthritis. |
| title | Analysis of T cell clones in rheumatoid arthritis. |
| title_full | Analysis of T cell clones in rheumatoid arthritis. |
| title_fullStr | Analysis of T cell clones in rheumatoid arthritis. |
| title_full_unstemmed | Analysis of T cell clones in rheumatoid arthritis. |
| title_short | Analysis of T cell clones in rheumatoid arthritis. |
| title_sort | analysis of t cell clones in rheumatoid arthritis |
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