CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.

Base excision repair (BER) is the major pathway for processing of simple lesions in DNA, including single-strand breaks, base damage, and base loss. The scaffold protein XRCC1, DNA polymerase beta, and DNA ligase IIIalpha play pivotal roles in BER. Although all these enzymes are essential for develo...

Detaylı Bibliyografya
Asıl Yazarlar:	Parsons, J, Tait, P, Finch, D, Dianova, I, Allinson, S, Dianov, G
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2008

Benzer Materyaller

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
Yazar:: Dianova, I, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Repair of abasic sites in DNA.
Yazar:: Dianov, G, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Co-ordination of base excision repair and genome stability.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

APE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanine.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Orchestration of base excision repair by controlling the rates of enzymatic activities.
Yazar:: Allinson, S, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

DNA base damage recognition and processing
Yazar:: Dianov, G, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

USP7/HAUSP stimulates repair of oxidative DNA lesions.
Yazar:: Khoronenkova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

DNA repair fidelity of base excision repair pathways in human cell extracts.
Yazar:: Zhang, Q, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

In vitro base excision repair using mammalian cell extracts.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks.
Yazar:: Woodhouse, B, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage
Yazar:: Khoronenkova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.
Yazar:: Khoronenkova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair.
Yazar:: Khoronenkova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?
Yazar:: Poletto, M, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

Exchangeability of mammalian DNA ligases between base excision repair pathways.
Yazar:: Sleeth, K, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.
Yazar:: Meisenberg, C, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
Yazar:: Yang, J, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Monitoring base excision repair by in vitro assays.
Yazar:: Dianov, G
Baskı/Yayın Bilgisi: (2003)

Base excision repair targets for cancer therapy.
Yazar:: Dianov, G
Baskı/Yayın Bilgisi: (2011)

Isolation of a small molecule inhibitor of DNA base excision repair.
Yazar:: Madhusudan, S, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
Yazar:: Ström, C, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Mammalian base excision repair: the forgotten archangel.
Yazar:: Dianov, G, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Targeting base excision repair to improve cancer therapies.
Yazar:: Sharma, R, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

DNA Damage and Base Excision Repair in Mitochondria and Their Role in Aging
Yazar:: Ricardo Gredilla
Baskı/Yayın Bilgisi: (2011-01-01)

Mechanism and regulation of DNA damage recognition in nucleotide excision repair
Yazar:: Masayuki Kusakabe, ve diğerleri
Baskı/Yayın Bilgisi: (2019-01-01)

The emerging role of Mule and ARF in the regulation of base excision repair.
Yazar:: Khoronenkova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

The emerging role of Mule and ARF in the regulation of base excision repair
Yazar:: Khoronenkova, S, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.
Yazar:: Alo Ray, ve diğerleri
Baskı/Yayın Bilgisi: (2016-01-01)

Regulation of DNA repair by ubiquitylation.
Yazar:: Dianov, G, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Co-ordination of DNA single strand break repair.
Yazar:: Dianov, G, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Base excision repair fidelity in normal and cancer cells.
Yazar:: Chan, K, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Base excision repair of radiation-induced DNA damage in mammalian cells
Yazar:: Cooper, S, ve diğerleri
Baskı/Yayın Bilgisi: (2013)