Delivering functional imaging on the MRI-linac: Current challenges and potential solutions

Magnetic resonance imaging (MRI) is a highly versatile imaging modality that can be used to measure features of the tumour microenvironment including cell death, proliferation, metabolism, angiogenesis, and hypoxia. Mapping and quantifying these pathophysiological features has the potential to alter...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Datta, A, Aznar, MC, Dubec, M, Parker, GJM, O'Connor, JPB
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2018
Beskrivning
Sammanfattning:Magnetic resonance imaging (MRI) is a highly versatile imaging modality that can be used to measure features of the tumour microenvironment including cell death, proliferation, metabolism, angiogenesis, and hypoxia. Mapping and quantifying these pathophysiological features has the potential to alter the use of adaptive radiotherapy planning. Although these methods are available for use on diagnostic machines, several challenges exist for implementing these functional MRI methods on the MRI-linear accelerators (linacs). This review considers these challenges and potential solutions.