Late-Stage Trifluoromethylation

Late-Stage Trifluoromethylation

<p>This thesis is concerned with the development of methodology for late-stage trifluoromethylation of complex molecules.</p> <p><strong>Chapter 1</strong> introduces the concept of late-stage trifluoromethylations and details the effect that substitution of a CF<sub...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Verhoog, S
Awduron Eraill:	Gouverneur, V
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2016

Eitemau Tebyg

18F-trifluoromethylation of unmodified peptides with 5-18F-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate
gan: Verhoog, S, et al.
Cyhoeddwyd: (2018)

Trifluoromethylation of allylsilanes under copper catalysis.
gan: Mizuta, S, et al.
Cyhoeddwyd: (2012)

Trifluoromethylation of allylsilanes under photoredox catalysis.
gan: Mizuta, S, et al.
Cyhoeddwyd: (2013)

Redox chemistry of trifluoromethyl sulfonium salts as CF3 radical sources
gan: Mizuta, S, et al.
Cyhoeddwyd: (2013)

Synthesis and trifluoromethylation of allylsilanes
gan: Galicia Lopez, O
Cyhoeddwyd: (2013)

Reaction of (trifluoromethyl)trimethylsilane with oxazolidin-5-ones: Synthesis of peptidic and nonpeptidic trifluoromethyl ketones
gan: Walter, M, et al.
Cyhoeddwyd: (1998)

Visible Light Promotes Cascade Trifluoromethylation/Cyclization, Leading to Trifluoromethylated Polycyclic Quinazolinones, Benzimidazoles and Indoles
gan: Ransong Ma, et al.
Cyhoeddwyd: (2022-12-01)

Copper-Catalyzed Trifluoromethylation of Alkoxypyridine Derivatives
gan: Nandor Gyorfi, et al.
Cyhoeddwyd: (2020-10-01)

Synthesis of Trifluoromethylated Monoterpene Amino Alcohols
gan: Polina A. Petrova, et al.
Cyhoeddwyd: (2022-10-01)

Langlois Reagent: An Efficient Trifluoromethylation Reagent
gan: K. Anusha, et al.
Cyhoeddwyd: (2023-02-01)

Nucleophilic trifluoromethylation of some polycyclic ketones
gan: Jarosław Romański, et al.
Cyhoeddwyd: (2007-03-01)

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides
gan: Cho, Eun Jin, et al.
Cyhoeddwyd: (2013)

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins
gan: Parsons, Andrew T., et al.
Cyhoeddwyd: (2013)

The Palladium-Catalyzed Trifluoromethylation of Vinyl Sulfonates
gan: Cho, Eun Jin, et al.
Cyhoeddwyd: (2013)

Gas/Liquid‐Phase Micro‐Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N‐Sulfinylimines
gan: Kazuki Hirano, et al.
Cyhoeddwyd: (2019-04-01)

Gas/Liquid‐Phase Micro‐Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N‐Sulfinylimines
gan: Kazuki Hirano, et al.
Cyhoeddwyd: (2019-04-01)

1-(Pyridin-2-yl)-2-[2-(trifluoromethyl)benzyl]-3-[2-(trifluoromethyl)phenyl]propan-1-one
gan: Muhammad Naveed Umar, et al.
Cyhoeddwyd: (2012-03-01)

Improved Synthesis of 2‑Trifluoromethyl-10-aminopropylphenothiazine: Making 2‑Trifluoromethyl-10-aminopropylphenothiazine Readily Available for Calmodulin Purification
gan: Josiah W. Johnson, et al.
Cyhoeddwyd: (2018-11-01)

Selective radical trifluoromethylation of native residues in proteins
gan: Imiołek, M, et al.
Cyhoeddwyd: (2018)

Visible-light-induced trifluoromethylation of allylic alcohols
gan: Li, Bowen, et al.
Cyhoeddwyd: (2022)

Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups
gan: Ita Hajdin, et al.
Cyhoeddwyd: (2023-04-01)

Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)-benzoates
gan: Jiřina Stolaříková, et al.
Cyhoeddwyd: (2013-03-01)

Methyl 2-[4-(trifluoromethyl)phenylsulfanyl]benzoate
gan: Thammarse S. Yamuna, et al.
Cyhoeddwyd: (2013-11-01)

Electrochemical O-trifluoromethylation of electron-deficient phenols
gan: Johannes Bernd, et al.
Cyhoeddwyd: (2021-12-01)

Synthesis of new triazole-based trifluoromethyl scaffolds
gan: Michela Martinelli, et al.
Cyhoeddwyd: (2008-05-01)

Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates
gan: Parsons, Andrew T., et al.
Cyhoeddwyd: (2013)

18F-trifluoromethanesulfinate enables direct C–H 18F-trifluoromethylation of native aromatic residues in peptides
gan: Kee, C, et al.
Cyhoeddwyd: (2020)

Highly diastereoselective synthesis of trifluoromethyl indolines by interceptive benzylic decarboxylative cycloaddition of nonvinyl, trifluoromethyl benzoxazinanones with sulfur ylides under palladium catalysis
gan: Punna, N, et al.
Cyhoeddwyd: (2018)

Catalytic asymmetric conjugate addition of mercaptans to β-substituted-β-trifluoromethyl oxazolidinone enoates : access to chiral trifluoromethylated tertiary thioethers and thiols
gan: Chen, Wenchao, et al.
Cyhoeddwyd: (2014)

Catalytic asymmetric conjugate addition of mercaptans to β-substituted-β-trifluoromethyl oxazolidinone enoates: access to chiral trifluoromethylated tertiary thioethers and thiols
gan: Chen, Wenchao, et al.
Cyhoeddwyd: (2014)

Controllable Synthesis of Trifluoromethyl- or <i>gem</i>-Difluorovinyl-containing Analogues of Neonicotinoids by the Reaction of α-(Trifluoromethyl)styrenes with 2-Nitroimino-imidazolidine
gan: Jingjing He, et al.
Cyhoeddwyd: (2023-04-01)

Tetrakis[3,5-bis-(trifluoromethyl)phenyl]silane
gan: Agnew, C, et al.
Cyhoeddwyd: (2006)

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature
gan: Feng, Chao, et al.
Cyhoeddwyd: (2013)

Introducing Weakly Ligated Tris(trifluoromethyl)copper(III)
gan: Dr. Vladimir Motornov, et al.
Cyhoeddwyd: (2024-03-01)

Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes
gan: Bo Fu, et al.
Cyhoeddwyd: (2021-11-01)

Trifluoromethylated Quinolone-Hydantoin Hybrids: Synthesis and Antibacterial Evaluation
gan: Akhil Mahajan, et al.
Cyhoeddwyd: (2022-07-01)

Bis(diisobutylammonium) tetrachloridobis[3-(trifluoromethyl)phenyl]stannate
gan: Xueqing Song, et al.
Cyhoeddwyd: (2023-10-01)

(E)-2-{[(2-(Trifluoromethyl)phenyl]iminomethyl}phenol
gan: Mustafa Odaba&#351;o&#287;lu, et al.
Cyhoeddwyd: (2012-03-01)

Synthesis and antimycobacterial activities of certain trifluoromethyl-aminoquinoline derivatives
gan: Alka Mital, et al.
Cyhoeddwyd: (2006-04-01)

3-Difluoromethyl-5-[4-(trifluoromethyl)phenyl]isoxazole
gan: Hui Zhao
Cyhoeddwyd: (2018-04-01)