Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability

The immunological synapse formed between a T‐cell and an antigen‐presenting cell is important for cell–cell communication during T‐cell‐mediated immune responses. Immunological synapse formation begins with stimulation of the T‐cell receptor (TCR). TCR microclusters are assembled and transported to...

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Hlavní autoři: Santos, L, Blair, D, Kumari, S, Cammer, M, Iskratsch, T, Herbin, O, Alexandropoulos, K, Dustin, M, Sheetz, M
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2016