A coalescent-based method for detecting and estimating recombination from gene sequences.

Determining the amount of recombination in the genealogical history of a sample of genes is important to both evolutionary biology and medical population genetics. However, recurrent mutation can produce patterns of genetic diversity similar to those generated by recombination and can bias estimates...

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Main Authors: McVean, G, Awadalla, P, Fearnhead, P
格式: Journal article
语言:English
出版: 2002