Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells.

Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells.

Replicating viruses have broad applications in biomedicine, notably in cancer virotherapy and in the design of attenuated vaccines; however, uncontrolled virus replication in vulnerable tissues can give pathology and often restricts the use of potent strains. Increased knowledge of tissue-selective...

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Bibliografiske detaljer
Main Authors:	Cawood, R, Chen, H, Carroll, F, Bazan-Peregrino, M, van Rooijen, N, Seymour, L
Format:	Journal article
Sprog:	English
Udgivet:	2009

Lignende værker

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af: Bazan-Peregrino, M, et al.
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af: Green, N, et al.
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Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome
af: Kahori Shimizu, et al.
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Comparison of molecular strategies for breast cancer virotherapy using oncolytic adenovirus.
af: Bazan-Peregrino, M, et al.
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af: Carlisle, R, et al.
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Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.
af: Lyons, M, et al.
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af: Weiheng Su, et al.
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af: Feng Huang, et al.
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af: Chen, H, et al.
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af: Chen, H, et al.
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af: Qiaoling Li, et al.
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Gene therapy targeting to tumor endothelium.
af: Bazan-Peregrino, M, et al.
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af: Graham, S, et al.
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