Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.

OBJECTIVE: Because most daily activities are conducted at submaximal exercise level, treatments are implemented to improve submaximal coronary artery blood flow (CABF). We sought to validate the reproducibility of cardiovascular magnetic resonance imaging measurements of submaximal CABF. METHODS: W...

Full description

Bibliographic Details
Main Authors: Dall'Armellina, E, Baugh, M, Morgan, T, Hamilton, C, Tan, P, Herrington, D, Link, K, Hundley, W
Format: Journal article
Language:English
Published: 2006
_version_ 1797106094198226944
author Dall'Armellina, E
Baugh, M
Morgan, T
Hamilton, C
Tan, P
Herrington, D
Link, K
Hundley, W
author_facet Dall'Armellina, E
Baugh, M
Morgan, T
Hamilton, C
Tan, P
Herrington, D
Link, K
Hundley, W
author_sort Dall'Armellina, E
collection OXFORD
description OBJECTIVE: Because most daily activities are conducted at submaximal exercise level, treatments are implemented to improve submaximal coronary artery blood flow (CABF). We sought to validate the reproducibility of cardiovascular magnetic resonance imaging measurements of submaximal CABF. METHODS: We measured CABF in the left anterior descending artery in 11 healthy postmenopausal women at rest and after submaximal bike exercise on 2 occasions 8 to 16 weeks apart. RESULTS: After exercise, CABF increased by 42% and 47% on the first and second examination, respectively. These changes in CABF in the 2 examinations were highly correlated (r=0.86). CONCLUSIONS: These data indicate that cardiovascular magnetic resonance assessments of CABF before and after submaximal exercise are feasible, reproducible, and consistent with those obtained invasively. In future studies, 24 patients would be needed per group to detect a 20% change of submaximal exercise blood flow at 80% power.
first_indexed 2024-03-07T06:56:49Z
format Journal article
id oxford-uuid:fe6a4b14-0c42-434c-8bf4-2a634177d89c
institution University of Oxford
language English
last_indexed 2024-03-07T06:56:49Z
publishDate 2006
record_format dspace
spelling oxford-uuid:fe6a4b14-0c42-434c-8bf4-2a634177d89c2022-03-27T13:36:15ZCardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fe6a4b14-0c42-434c-8bf4-2a634177d89cEnglishSymplectic Elements at Oxford2006Dall'Armellina, EBaugh, MMorgan, THamilton, CTan, PHerrington, DLink, KHundley, W OBJECTIVE: Because most daily activities are conducted at submaximal exercise level, treatments are implemented to improve submaximal coronary artery blood flow (CABF). We sought to validate the reproducibility of cardiovascular magnetic resonance imaging measurements of submaximal CABF. METHODS: We measured CABF in the left anterior descending artery in 11 healthy postmenopausal women at rest and after submaximal bike exercise on 2 occasions 8 to 16 weeks apart. RESULTS: After exercise, CABF increased by 42% and 47% on the first and second examination, respectively. These changes in CABF in the 2 examinations were highly correlated (r=0.86). CONCLUSIONS: These data indicate that cardiovascular magnetic resonance assessments of CABF before and after submaximal exercise are feasible, reproducible, and consistent with those obtained invasively. In future studies, 24 patients would be needed per group to detect a 20% change of submaximal exercise blood flow at 80% power.
spellingShingle Dall'Armellina, E
Baugh, M
Morgan, T
Hamilton, C
Tan, P
Herrington, D
Link, K
Hundley, W
Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.
title Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.
title_full Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.
title_fullStr Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.
title_full_unstemmed Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.
title_short Cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise.
title_sort cardiovascular magnetic resonance measurement of coronary arterial blood flow at rest and after submaximal exercise
work_keys_str_mv AT dallarmellinae cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT baughm cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT morgant cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT hamiltonc cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT tanp cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT herringtond cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT linkk cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise
AT hundleyw cardiovascularmagneticresonancemeasurementofcoronaryarterialbloodflowatrestandaftersubmaximalexercise