Stromal uptake and transmission of acid is a pathway for venting cancer cell-generated acid

Stromal uptake and transmission of acid is a pathway for venting cancer cell-generated acid

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Proliferation and invasion of cancer cells require favorable pH, yet potentially toxic quantities of acid are produced metabolically. Membrane-bound transporters extrude acid from cancer cells, but little is known about the mechanisms that handle acid once it is released into the poorly-perfused ext...

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Bibliographic Details
Main Authors:	Hulikova, A, Black, N, Hsia, L, Wilding, J, Bodmer, W, Swietach, P
Format:	Journal article
Published:	National Academy of Sciences 2016

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