Validating discovered Cis-acting regulatory genetic variants: application of an allele specific expression approach to HapMap populations

BACKGROUND: Localising regulatory variants that control gene expression is a challenge for genome research. Several studies have recently identified non-coding polymorphisms associated with inter-individual differences in gene expression. These approaches rely on the identification of signals of ass...

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Hlavní autoři: Campino, S, Forton, J, Raj, S, Mohr, B, Auburn, S, Fry, A, Mangano, V, Vandiedonck, C, Richardson, A, Rockett, K, Clark, T, Kwiatkowski, D
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2008