Establishment and maintenance of the DNA methylation pattern in the human alpha-globin cluster

<p>DNA methylation is an epigenetic modification that plays an important role in development and differentiation. The patterns of DNA methylation are largely established in early embryogenesis and maintained during development. Abnormal DNA methylation patterns have been associated with many h...

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Bibliographic Details
Main Author: Gaentzsch, R
Other Authors: Gibbons, R
Format: Thesis
Language:English
Published: 2013
Subjects: