Typhoid epidemiology, diagnostics and the human challenge model.

Typhoid epidemiology, diagnostics and the human challenge model.

PURPOSE OF REVIEW: Infection caused by ingestion of human-restricted Salmonella enterica serovars Typhi and Paratyphi predominantly affects the most impoverished sections of society. In this review, we describe recent advances made in estimating the burden of illness and the important role improved...

ver descrição completa

Detalhes bibliográficos
Principais autores:	Darton, T, Blohmke, C, Pollard, A
Formato:	Journal article
Idioma:	English
Publicado em:	2014

Registros relacionados

Application of a challenge model to assess the protective efficacy of oral typhoid vaccines in humans
por: Darton, T, et al.
Publicado em: (2014)

Why the development of effective typhoid control measures requires the use of human challenge studies.
por: Jones, C, et al.
Publicado em: (2014)

Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model
por: Fresnay, S, et al.
Publicado em: (2017)

Advancing the management and control of typhoid fever: A review of the historical role of human challenge studies
por: Waddington, C, et al.
Publicado em: (2014)

Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia.
por: Darton, T, et al.
Publicado em: (2017)

Why the development of effective typhoid control measures requires the use of human challenge studies
por: Claire eJones, et al.
Publicado em: (2014-12-01)

Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
por: McArthur, M, et al.
Publicado em: (2015)

Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
por: Gibani, M, et al.
Publicado em: (2019)

Rapidly escalating hepcidin and associated serum iron starvation are features of the acute response to typhoid infection in humans
por: Darton, T, et al.
Publicado em: (2015)

Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies.
por: Waddington, C, et al.
Publicado em: (2014)

Oral challenge with wild-type Salmonella Typhi induces distinct changes in B cell subsets in individuals who develop typhoid disease.
por: Toapanta, F, et al.
Publicado em: (2016)

Oral wild-type Salmonella Typhi challenge induces activation of circulating monocytes and dendritic cells in individuals who develop typhoid disease
por: Toapanta, F, et al.
Publicado em: (2015)

Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans
por: Fresnay, S, et al.
Publicado em: (2016)

Host restriction, pathogenesis and chronic carriage of typhoidal Salmonella
por: J Barton, A, et al.
Publicado em: (2021)

Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
por: Monica A McArthur, et al.
Publicado em: (2015-05-01)

Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans.
por: Thomas C Darton, et al.
Publicado em: (2015-09-01)

Salmonella typhi bactericidal antibodies reduce disease severity but do not protect against typhoid fever in a controlled human infection model
por: Juel, H, et al.
Publicado em: (2018)

Transcriptomics in human challenge models
por: Barton, A, et al.
Publicado em: (2017)

Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever
por: Salerno-Gonçalves, R, et al.
Publicado em: (2022)

Demonstration of primary and asymptomatic DNAaemia in participants challenged with Salmonella Typhi (Quailes strain) during the development of a human model of typhoid infection
por: Darton, T, et al.
Publicado em: (2012)

Induction of cell cycle and NK cell responses by live-attenuated oral vaccines against typhoid fever
por: Blohmke, CJ, et al.
Publicado em: (2017)

Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines against Typhoid Fever
por: Christoph J. Blohmke, et al.
Publicado em: (2017-10-01)

Design, recruitment, and microbiological considerations in human challenge studies.
por: Darton, T, et al.
Publicado em: (2015)

Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease.
por: Franklin R Toapanta, et al.
Publicado em: (2016-06-01)

Using a human challenge model of infection to measure vaccine efficacy: a randomised, controlled trial comparing the typhoid vaccines M01ZH09 with placebo and Ty21a
por: Darton, T, et al.
Publicado em: (2016)

Control of invasive Salmonella disease in Africa: is there a role for human challenge models?
por: Gibani, M, et al.
Publicado em: (2015)

Identification of Novel Serodiagnostic Signatures of Typhoid Fever Using a Salmonella Proteome Array
por: Thomas C. Darton, et al.
Publicado em: (2017-09-01)

Typhoid vaccine landscape
por: Pollard, A
Publicado em: (2012)

Identification of novel serodiagnostic signatures of typhoid fever using a salmonella proteome array
por: Darton, T, et al.
Publicado em: (2017)

Typhoid conjugate vaccines: a step towards typhoid control
por: Shakya, M, et al.
Publicado em: (2024)

Typhoid: From past to future
por: Kirchhelle, C, et al.
Publicado em: (2019)

Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria
por: Toapanta, FR, et al.
Publicado em: (2024)

The Typhoid Vaccine Acceleration Consortium (TyVAC): vaccine effectiveness study designs: accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26-27 October 2016, Oxford, UK
por: Meiring, J, et al.
Publicado em: (2017)

The current status of enteric fever diagnostics and implications for disease control
por: Baker, S, et al.
Publicado em: (2020)

Concurrent malaria and typhoid fever in the tropics: the diagnostic challenges and public health implications
por: C.J. Uneke
Publicado em: (2008-05-01)

Understanding typhoid disease; a controlled human infection model of typhoid fever
por: Waddington, C, et al.
Publicado em: (2014)

Searching for the elusive typhoid diagnostic
por: Baker, S, et al.
Publicado em: (2010)

Searching for the elusive typhoid diagnostic
por: Baker Stephen, et al.
Publicado em: (2010-03-01)

Solving the typhoid diagnostics conundrum
por: Baker, S
Publicado em: (2012)

Case report: Typhoid fever complicated by ileal perforation in an urban slum of Dhaka, Bangladesh
por: Khanam, F, et al.
Publicado em: (2021)