Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape.
Effective preventive and therapeutic intervention in individuals exposed to or infected with human immunodeficiency virus (HIV) depends, in part, on a clear understanding of the interactions between the virus and those elements of the host immune response which control viral replication. Recent adva...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2000
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| _version_ | 1826307178559963136 |
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| author | Sewell, A Price, D Oxenius, A Kelleher, A Phillips, R |
| author_facet | Sewell, A Price, D Oxenius, A Kelleher, A Phillips, R |
| author_sort | Sewell, A |
| collection | OXFORD |
| description | Effective preventive and therapeutic intervention in individuals exposed to or infected with human immunodeficiency virus (HIV) depends, in part, on a clear understanding of the interactions between the virus and those elements of the host immune response which control viral replication. Recent advances have provided compelling evidence that cytotoxic T lymphocytes (CTLs) constitute an essential component of protective antiretroviral immunity. Here, we review briefly the significance of this work in the context of previous studies, and outline the mechanisms through which HIV evades CTL activity. |
| first_indexed | 2024-03-07T06:59:02Z |
| format | Journal article |
| id | oxford-uuid:ff1a5edd-aeed-4dcf-896a-96e45adc342a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:59:02Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:ff1a5edd-aeed-4dcf-896a-96e45adc342a2022-03-27T13:42:04ZCytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ff1a5edd-aeed-4dcf-896a-96e45adc342aEnglishSymplectic Elements at Oxford2000Sewell, APrice, DOxenius, AKelleher, APhillips, REffective preventive and therapeutic intervention in individuals exposed to or infected with human immunodeficiency virus (HIV) depends, in part, on a clear understanding of the interactions between the virus and those elements of the host immune response which control viral replication. Recent advances have provided compelling evidence that cytotoxic T lymphocytes (CTLs) constitute an essential component of protective antiretroviral immunity. Here, we review briefly the significance of this work in the context of previous studies, and outline the mechanisms through which HIV evades CTL activity. |
| spellingShingle | Sewell, A Price, D Oxenius, A Kelleher, A Phillips, R Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape. |
| title | Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape. |
| title_full | Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape. |
| title_fullStr | Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape. |
| title_full_unstemmed | Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape. |
| title_short | Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape. |
| title_sort | cytotoxic t lymphocyte responses to human immunodeficiency virus control and escape |
| work_keys_str_mv | AT sewella cytotoxictlymphocyteresponsestohumanimmunodeficiencyviruscontrolandescape AT priced cytotoxictlymphocyteresponsestohumanimmunodeficiencyviruscontrolandescape AT oxeniusa cytotoxictlymphocyteresponsestohumanimmunodeficiencyviruscontrolandescape AT kellehera cytotoxictlymphocyteresponsestohumanimmunodeficiencyviruscontrolandescape AT phillipsr cytotoxictlymphocyteresponsestohumanimmunodeficiencyviruscontrolandescape |