p53 coordinates base excision repair to prevent genomic instability

p53 coordinates base excision repair to prevent genomic instability

DNA constantly undergoes chemical modification due to endogenous and exogenous mutagens. The DNA base excision repair (BER) pathway is the frontline mechanism handling the majority of these lesions, and primarily involves a DNA incision and subsequent resealing step. It is imperative that these proc...

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Chi tiết về thư mục
Những tác giả chính:	Poletto, M, Legrand, A, Fletcher, S, Dianov, G
Định dạng:	Journal article
Được phát hành:	Oxford University Press 2016

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