Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP.
L-DMDP, prepared from D-gulonolactone, is a highly specific inhibitor of a number of plant and mammalian alpha-glucosidases [between 2 and 4 orders of magnitude more potent than the enantiomeric natural product DMDP] but is not an inhibitor of bacterial and yeast alpha-glucosidases. Additionally N-b...
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Bibliographic Details
Main Authors: |
Yu, C,
Asano, N,
Ikeda, K,
Wang, M,
Butters, T,
Wormald, M,
Dwek, R,
Winters, A,
Nash, R,
Fleet, G |
Format: | Journal article
|
Language: | English |
Published: |
2004
|