Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure.
Phosphorylation is the most common posttranslational modification of the α-crystallins in the human lens. These phosphorylated forms are not only important because of their abundance in aging lenses and the implications for cataract but also because they have been identified in patients with degener...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
American Society for Biochemistry and Molecular Biology
2004
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