Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice.

Background: Identifying genes that are essential for mouse embryonic development and survival through term is a powerful and unbiased way to discover possible genetic determinants of human developmental disorders. Characterising the changes in mouse embryos that result from ablation of lethal genes...

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Бібліографічні деталі
Автори: Wilson, R, Geyer, S, Reissig, L, Rose, J, Szumska, D, Hardman, E, Prin, F, McGuire, C, Ramirez-Solis, R, White, J, Galli, A, Tudor, C, Tuck, E, Mazzeo, C, Smith, J, Robertson, E, Adams, D, Mohun, T, Weninger, W
Формат: Journal article
Мова:English
Опубліковано: F1000Research 2017