In vivo negative regulation of SARS-CoV-2 receptor, ACE2, by interferons and its genetic control

In vivo negative regulation of SARS-CoV-2 receptor, ACE2, by interferons and its genetic control

<br><strong>Background: </strong>Angiotensin I converting enzyme 2 (ACE2) is a receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and differences in its expression may affect susceptibility to infection. <br><strong>Methods: </strong>We...

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Hlavní autoři: Ansari, A, Marchi, E, Ramamurthy, N, Aschenbrenner, D, Morgan, S, Hackstein, C-P, Lin, S-K, Bowden, R, Sharma, E, Pedergnana, V, Venkateswaran, S, Kugathasan, S, Mo, A, Gibson, G, Cooke, G, McLauchlan, J, Baillie, JK, Teichmann, S, Mentzer, A, Knight, J, Todd, J, Hinks, T, Barnes, E, Klenerman, P, Uhlig, H
Další autoři: STOP-HCV Consortium
Médium: Journal article
Jazyk:English
Vydáno: F1000 Research Ltd 2021

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