Extrusion without a motor: a new take on the loop extrusion model of genome organization

Chromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangement of the CTCF binding motifs that stabilize loops, and extrusion is the only model to date which can explain this. Howe...

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Bibliographic Details
Main Authors: Brackley, CA, Johnson, J, Michieletto, D, Morozov, AN, Nicodemi, M, Cook, PR, Marenduzzo, D
Format: Journal article
Language:English
Published: Taylor and Francis 2018

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