Extrusion without a motor: a new take on the loop extrusion model of genome organization
Chromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangement of the CTCF binding motifs that stabilize loops, and extrusion is the only model to date which can explain this. Howe...
Main Authors: | Brackley, CA, Johnson, J, Michieletto, D, Morozov, AN, Nicodemi, M, Cook, PR, Marenduzzo, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Taylor and Francis
2018
|
Similar Items
-
Nonequilibrium chromosome looping via molecular slip links
by: Brackley, C, et al.
Published: (2017) -
Genome organization by loop extrusion
by: Goloborodko, Anton.
Published: (2020) -
Fluidification of entangled polymers by loop extrusion
by: Filippo Conforto, et al.
Published: (2024-08-01) -
A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture
by: Imakaev, Maksim Viktorovich, et al.
Published: (2020) -
Chromatin organization by an interplay of loop extrusion and compartmental segregation
by: Fudenberg, Geoffrey, et al.
Published: (2019)