Identifying regulators of chronic myeloid leukaemic (CML) stem cell quiescence and discovering effective novel therapies for CML relapse

<p>Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm characterised by the presence of Philadelphia (Ph) chromosome. The standard treatment is tyrosine kinase inhibitors (TKI), while they achieve remission in many patients, the majority will relapse on cessation of therapy. This...

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Bibliographic Details
Main Author: Xu, Z
Other Authors: Mead, A
Format: Thesis
Language:English
Published: 2022