Functional regulation of p73 and p63: development and cancer.

The transcription factor and tumour suppressor p53 and its two homologues p63 and p73 form a family of proteins. p63 and p73 show much greater molecular complexity than p53 because they are expressed both as multiple alternatively spliced C-terminal isoforms, and as N-terminally deleted, dominant-ne...

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Autori principali: Melino, G, Lu, X, Gasco, M, Crook, T, Knight, R
Natura: Journal article
Lingua:English
Pubblicazione: 2003