Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal

Poly(ADP-ribosyl)ation (PAR) is a versatile and complex posttranslational modification composed of repeating units of ADP-ribose arranged into linear or branched polymers. This scaffold is linked to the regulation of many of cellular processes including the DNA damage response, alteration of chromat...

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Autors principals: Rack, JGM, Liu, Q, Zorzini, V, Voorneveld, J, Ariza, A, Honarmand Ebrahimi, K, Reber, JM, Krassnig, SC, Ahel, D, van der Marel, GA, Mangerich, A, McCullagh, JSO, Filippov, DV, Ahel, I
Format: Journal article
Idioma:English
Publicat: Springer Nature 2021