Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract
Ageratum conyzoides or ‘Billy Goat Weed’ is a weed distributed in many tropical and subtropical countries. It is widely utilized in traditional medicine by various cultures worldwide. The leaf, stem, root and flower of A. conyzoides was used to evaluate its chemical profile. Their extract exhibit a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2019
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| Online Access: | http://journalarticle.ukm.my/14719/1/48_04_15.pdf |
| _version_ | 1796932126610817024 |
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| author | Sirikunya Sayompark, Sopita Tangpiriyavaree, Yupa Khongprik, Khanitta Meepradit, |
| author_facet | Sirikunya Sayompark, Sopita Tangpiriyavaree, Yupa Khongprik, Khanitta Meepradit, |
| author_sort | Sirikunya Sayompark, |
| collection | UKM |
| description | Ageratum conyzoides or ‘Billy Goat Weed’ is a weed distributed in many tropical and subtropical countries. It is widely utilized in traditional medicine by various cultures worldwide. The leaf, stem, root and flower of A. conyzoides was used to evaluate its chemical profile. Their extract exhibit a wide range of biological and pharmacological activities such as antiinflammatory, anti-allergic, analgesic, antifungal, and anti-bacterial activities have been recorded. The objectives of the study
were to evaluate the phytochemical screening tests of ethanolic extract of A. conyzoides and finally, the A. conyzoides extract
was developed in Gel formulation. The A. conyzoides gel formulation was studied the stability at 45°C and heating/cooling
condition, and then its appearance, viscosity, and pH value were determined. The presence phytochemical components of A.
conyzoides extract include alkaloids, tannins, flavonoids and phenols. The AC-6 formulation was showed good physical
properties: appearance, viscosity, and pH value by comparing it with marketed Diclofenac gel. The further study should be
evaluated for anti-inflammatory and analgesic potency by animal paradigms, which may be helpful in developing novel new
drugs. |
| first_indexed | 2024-03-06T04:28:11Z |
| format | Article |
| id | ukm.eprints-14719 |
| institution | Universiti Kebangsaan Malaysia |
| language | English |
| last_indexed | 2024-03-06T04:28:11Z |
| publishDate | 2019 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | dspace |
| spelling | ukm.eprints-147192020-06-03T00:51:50Z http://journalarticle.ukm.my/14719/ Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract Sirikunya Sayompark, Sopita Tangpiriyavaree, Yupa Khongprik, Khanitta Meepradit, Ageratum conyzoides or ‘Billy Goat Weed’ is a weed distributed in many tropical and subtropical countries. It is widely utilized in traditional medicine by various cultures worldwide. The leaf, stem, root and flower of A. conyzoides was used to evaluate its chemical profile. Their extract exhibit a wide range of biological and pharmacological activities such as antiinflammatory, anti-allergic, analgesic, antifungal, and anti-bacterial activities have been recorded. The objectives of the study were to evaluate the phytochemical screening tests of ethanolic extract of A. conyzoides and finally, the A. conyzoides extract was developed in Gel formulation. The A. conyzoides gel formulation was studied the stability at 45°C and heating/cooling condition, and then its appearance, viscosity, and pH value were determined. The presence phytochemical components of A. conyzoides extract include alkaloids, tannins, flavonoids and phenols. The AC-6 formulation was showed good physical properties: appearance, viscosity, and pH value by comparing it with marketed Diclofenac gel. The further study should be evaluated for anti-inflammatory and analgesic potency by animal paradigms, which may be helpful in developing novel new drugs. Penerbit Universiti Kebangsaan Malaysia 2019-11 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/14719/1/48_04_15.pdf Sirikunya Sayompark, and Sopita Tangpiriyavaree, and Yupa Khongprik, and Khanitta Meepradit, (2019) Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract. Malaysian Applied Biology, 48 (4). pp. 115-120. ISSN 0126-8643 http://www.mabjournal.com/index.php?option=com_content&view=article&id=946&catid=59:current-view&Itemid=56 |
| spellingShingle | Sirikunya Sayompark, Sopita Tangpiriyavaree, Yupa Khongprik, Khanitta Meepradit, Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract |
| title | Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract |
| title_full | Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract |
| title_fullStr | Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract |
| title_full_unstemmed | Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract |
| title_short | Development and evaluation of stability of gel formulation containing Ageratum conyzoides extract |
| title_sort | development and evaluation of stability of gel formulation containing ageratum conyzoides extract |
| url | http://journalarticle.ukm.my/14719/1/48_04_15.pdf |
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