Clinical significance of blood supply of the fornix of brain: a cadaveric study

Transient ischemic attack (TIA) of the fornix causes a spectrum of memory deficits, which increases the contributions of vascular disease to dementia which is known as early-onset dementia. As the fornix, the white matter bundle, serves as the major efferent pathway connecting the hippocampus with o...

Full description

Bibliographic Details
Main Authors: Patcharaporn Srisaikaew, Tanat Vaniyapong, Srijit Das, Pasuk Mahhakranukrauh
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2020
Online Access:http://journalarticle.ukm.my/14772/1/ARTIKEL%2018.pdf
_version_ 1796932136083652608
author Patcharaporn Srisaikaew,
Tanat Vaniyapong,
Srijit Das,
Pasuk Mahhakranukrauh,
author_facet Patcharaporn Srisaikaew,
Tanat Vaniyapong,
Srijit Das,
Pasuk Mahhakranukrauh,
author_sort Patcharaporn Srisaikaew,
collection UKM
description Transient ischemic attack (TIA) of the fornix causes a spectrum of memory deficits, which increases the contributions of vascular disease to dementia which is known as early-onset dementia. As the fornix, the white matter bundle, serves as the major efferent pathway connecting the hippocampus with other human limbic structures, a variety of lesions that damage the fornix could lead to significant memory impairment. Therefore, the blood supply of fornix is a concern. This study aims to study the arterial supply of fornix. Thirty fresh human cadaveric heads were used. They were preserved by the mixture of fixation solution for fornix anatomical dissection and injected with coloured latex solution for visualization of cerebral vasculature through 6 critical steps of approaches. The result showed that the fimbriae of fornix were mainly supplied by the branches of posterior cerebral artery (PCA) and two cases were found to have the anastomoses of those branches with the choroidal artery (ChA). The proposed technique confirmed the ability of coloration of human cerebral vasculature by using colored latex solution which penetrated into cerebral small vessels leading to a precise understanding of the arterial supply of fornix in human brain which is essential for neurosurgeon, neurosurgical training and researchers.
first_indexed 2024-03-06T04:28:21Z
format Article
id ukm.eprints-14772
institution Universiti Kebangsaan Malaysia
language English
last_indexed 2024-03-06T04:28:21Z
publishDate 2020
publisher Penerbit Universiti Kebangsaan Malaysia
record_format dspace
spelling ukm.eprints-147722020-06-22T08:49:04Z http://journalarticle.ukm.my/14772/ Clinical significance of blood supply of the fornix of brain: a cadaveric study Patcharaporn Srisaikaew, Tanat Vaniyapong, Srijit Das, Pasuk Mahhakranukrauh, Transient ischemic attack (TIA) of the fornix causes a spectrum of memory deficits, which increases the contributions of vascular disease to dementia which is known as early-onset dementia. As the fornix, the white matter bundle, serves as the major efferent pathway connecting the hippocampus with other human limbic structures, a variety of lesions that damage the fornix could lead to significant memory impairment. Therefore, the blood supply of fornix is a concern. This study aims to study the arterial supply of fornix. Thirty fresh human cadaveric heads were used. They were preserved by the mixture of fixation solution for fornix anatomical dissection and injected with coloured latex solution for visualization of cerebral vasculature through 6 critical steps of approaches. The result showed that the fimbriae of fornix were mainly supplied by the branches of posterior cerebral artery (PCA) and two cases were found to have the anastomoses of those branches with the choroidal artery (ChA). The proposed technique confirmed the ability of coloration of human cerebral vasculature by using colored latex solution which penetrated into cerebral small vessels leading to a precise understanding of the arterial supply of fornix in human brain which is essential for neurosurgeon, neurosurgical training and researchers. Penerbit Universiti Kebangsaan Malaysia 2020-02 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/14772/1/ARTIKEL%2018.pdf Patcharaporn Srisaikaew, and Tanat Vaniyapong, and Srijit Das, and Pasuk Mahhakranukrauh, (2020) Clinical significance of blood supply of the fornix of brain: a cadaveric study. Sains Malaysiana, 49 (2). pp. 399-404. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid49bil2_2020/KandunganJilid49Bil2_2020.html
spellingShingle Patcharaporn Srisaikaew,
Tanat Vaniyapong,
Srijit Das,
Pasuk Mahhakranukrauh,
Clinical significance of blood supply of the fornix of brain: a cadaveric study
title Clinical significance of blood supply of the fornix of brain: a cadaveric study
title_full Clinical significance of blood supply of the fornix of brain: a cadaveric study
title_fullStr Clinical significance of blood supply of the fornix of brain: a cadaveric study
title_full_unstemmed Clinical significance of blood supply of the fornix of brain: a cadaveric study
title_short Clinical significance of blood supply of the fornix of brain: a cadaveric study
title_sort clinical significance of blood supply of the fornix of brain a cadaveric study
url http://journalarticle.ukm.my/14772/1/ARTIKEL%2018.pdf
work_keys_str_mv AT patcharapornsrisaikaew clinicalsignificanceofbloodsupplyofthefornixofbrainacadavericstudy
AT tanatvaniyapong clinicalsignificanceofbloodsupplyofthefornixofbrainacadavericstudy
AT srijitdas clinicalsignificanceofbloodsupplyofthefornixofbrainacadavericstudy
AT pasukmahhakranukrauh clinicalsignificanceofbloodsupplyofthefornixofbrainacadavericstudy