Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report
Bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry (DXA) is important in diagnosing osteoporosis. Precision error of DXA is a useful measure to determine a true change in BMD value. This study aimed to investigate the short-term coefficient of variance of Hologic Discovery QD...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2020
|
| Online Access: | http://journalarticle.ukm.my/15108/1/6_ms0316_pdf_60643.pdf |
| _version_ | 1796932190924177408 |
|---|---|
| author | Subramaniam S, Mohamad NV, Chan, CY Ima Nirwana Soelaiman, Chin, Kok Yong |
| author_facet | Subramaniam S, Mohamad NV, Chan, CY Ima Nirwana Soelaiman, Chin, Kok Yong |
| author_sort | Subramaniam S, |
| collection | UKM |
| description | Bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry (DXA) is important in diagnosing osteoporosis. Precision error of DXA is a useful measure to determine a true change in BMD value. This study aimed to investigate the short-term coefficient of variance of Hologic Discovery QDR Wi DXA machine. The lumbar spine and hip BMD of fifteen healthy volunteers (mean age: 30.67 + 10.41 years) and the whole body BMD of fifteen female Sprague-Dawley rats (aged three months old) were scanned using Hologic Discovery QDR Wi DXA machine. Each volunteer and rat underwent triplicate scans to assess the reproducibility of BMD values. The interval between the scans ranged within 1 to 12 weeks for human subjects. For animal samples, the scans were repeated on the same day after repositioning. The precision error was expressed as a percentage coefficient of variance (%CV). The %CV obtained for lumbar spine and hip BMD for human were 1.8% and 1.2%, respectively. The %CV for whole body BMD of rats was 1.4%. The short-term CV demonstrated for both human and animal in the present study were comparable. The precision error of DXA must be monitored to ensure optimal performance of the device. |
| first_indexed | 2024-03-06T04:29:11Z |
| format | Article |
| id | ukm.eprints-15108 |
| institution | Universiti Kebangsaan Malaysia |
| language | English |
| last_indexed | 2024-03-06T04:29:11Z |
| publishDate | 2020 |
| publisher | Pusat Perubatan Universiti Kebangsaan Malaysia |
| record_format | dspace |
| spelling | ukm.eprints-151082020-08-26T01:14:12Z http://journalarticle.ukm.my/15108/ Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report Subramaniam S, Mohamad NV, Chan, CY Ima Nirwana Soelaiman, Chin, Kok Yong Bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry (DXA) is important in diagnosing osteoporosis. Precision error of DXA is a useful measure to determine a true change in BMD value. This study aimed to investigate the short-term coefficient of variance of Hologic Discovery QDR Wi DXA machine. The lumbar spine and hip BMD of fifteen healthy volunteers (mean age: 30.67 + 10.41 years) and the whole body BMD of fifteen female Sprague-Dawley rats (aged three months old) were scanned using Hologic Discovery QDR Wi DXA machine. Each volunteer and rat underwent triplicate scans to assess the reproducibility of BMD values. The interval between the scans ranged within 1 to 12 weeks for human subjects. For animal samples, the scans were repeated on the same day after repositioning. The precision error was expressed as a percentage coefficient of variance (%CV). The %CV obtained for lumbar spine and hip BMD for human were 1.8% and 1.2%, respectively. The %CV for whole body BMD of rats was 1.4%. The short-term CV demonstrated for both human and animal in the present study were comparable. The precision error of DXA must be monitored to ensure optimal performance of the device. Pusat Perubatan Universiti Kebangsaan Malaysia 2020 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/15108/1/6_ms0316_pdf_60643.pdf Subramaniam S, and Mohamad NV, and Chan, CY and Ima Nirwana Soelaiman, and Chin, Kok Yong (2020) Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report. Medicine & Health, 15 (1). pp. 70-77. ISSN 2289-5728 http://www.medicineandhealthukm.com/toc/15/1 |
| spellingShingle | Subramaniam S, Mohamad NV, Chan, CY Ima Nirwana Soelaiman, Chin, Kok Yong Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report |
| title | Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report |
| title_full | Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report |
| title_fullStr | Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report |
| title_full_unstemmed | Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report |
| title_short | Calculating in-vivo short-term precision error of dual-energy x-ray absorptiometry in human and animal: a technical report |
| title_sort | calculating in vivo short term precision error of dual energy x ray absorptiometry in human and animal a technical report |
| url | http://journalarticle.ukm.my/15108/1/6_ms0316_pdf_60643.pdf |
| work_keys_str_mv | AT subramaniams calculatinginvivoshorttermprecisionerrorofdualenergyxrayabsorptiometryinhumanandanimalatechnicalreport AT mohamadnv calculatinginvivoshorttermprecisionerrorofdualenergyxrayabsorptiometryinhumanandanimalatechnicalreport AT chancy calculatinginvivoshorttermprecisionerrorofdualenergyxrayabsorptiometryinhumanandanimalatechnicalreport AT imanirwanasoelaiman calculatinginvivoshorttermprecisionerrorofdualenergyxrayabsorptiometryinhumanandanimalatechnicalreport AT chinkokyong calculatinginvivoshorttermprecisionerrorofdualenergyxrayabsorptiometryinhumanandanimalatechnicalreport |