Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis

Acute retinal necrosis (ARN) is a rare, blinding disease that typically affects adults. However, in this case report, we highlight the diagnosis, management and outcome of herpes simplex acute retinal necrosis in a 13-year-old healthy girl, who presented with painful right eye, redness and blurri...

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Main Authors: Sherina Quay, Rosiah M, Mushawiahti Mustapha
Format: Article
Language:English
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/15571/1/26_ms0320_pdf_26801.pdf
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author Sherina Quay,
Rosiah M,
Mushawiahti Mustapha,
author_facet Sherina Quay,
Rosiah M,
Mushawiahti Mustapha,
author_sort Sherina Quay,
collection UKM
description Acute retinal necrosis (ARN) is a rare, blinding disease that typically affects adults. However, in this case report, we highlight the diagnosis, management and outcome of herpes simplex acute retinal necrosis in a 13-year-old healthy girl, who presented with painful right eye, redness and blurring of vision for one week. Examination of the right eye showed features of granulomatous panuveitis. Optic disc was swollen and retina appeared pale. There were multiple patches of retinitis and haemorrhages at mid-periphery of the fundus with inferior serous detachment observed. Rapidly progressive inflammation in just four days along with secondary cataract that obscured fundus view, imposed greater challenge to the diagnosis and management. Intravenous acyclovir 300mg, 3 times a day was initiated promptly while vitreous fluid was sent for polymerase chain reaction, which identified Herpes Simplex Virus-1. Inflammation improved, but she developed vitreous haemorrhage secondary to proliferative retinopathy, which required panretinal photocoagulation. ARN is therefore, principally a clinical diagnosis and high index of suspicion is crucial particularly, in children for prompt diagnosis and treatment. Complications should also be addressed timely to improve the chances of preserving vision.
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spelling ukm.eprints-155712020-11-04T16:37:36Z http://journalarticle.ukm.my/15571/ Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis Sherina Quay, Rosiah M, Mushawiahti Mustapha, Acute retinal necrosis (ARN) is a rare, blinding disease that typically affects adults. However, in this case report, we highlight the diagnosis, management and outcome of herpes simplex acute retinal necrosis in a 13-year-old healthy girl, who presented with painful right eye, redness and blurring of vision for one week. Examination of the right eye showed features of granulomatous panuveitis. Optic disc was swollen and retina appeared pale. There were multiple patches of retinitis and haemorrhages at mid-periphery of the fundus with inferior serous detachment observed. Rapidly progressive inflammation in just four days along with secondary cataract that obscured fundus view, imposed greater challenge to the diagnosis and management. Intravenous acyclovir 300mg, 3 times a day was initiated promptly while vitreous fluid was sent for polymerase chain reaction, which identified Herpes Simplex Virus-1. Inflammation improved, but she developed vitreous haemorrhage secondary to proliferative retinopathy, which required panretinal photocoagulation. ARN is therefore, principally a clinical diagnosis and high index of suspicion is crucial particularly, in children for prompt diagnosis and treatment. Complications should also be addressed timely to improve the chances of preserving vision. Pusat Perubatan Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/15571/1/26_ms0320_pdf_26801.pdf Sherina Quay, and Rosiah M, and Mushawiahti Mustapha, (2019) Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis. Medicine & Health, 14 (2). pp. 271-277. ISSN 2289-5728 https://www.medicineandhealthukm.com/toc/14/2
spellingShingle Sherina Quay,
Rosiah M,
Mushawiahti Mustapha,
Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis
title Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis
title_full Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis
title_fullStr Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis
title_full_unstemmed Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis
title_short Vitreous haemorrhage: a consequence of herpes simplex acute retinal necrosis
title_sort vitreous haemorrhage a consequence of herpes simplex acute retinal necrosis
url http://journalarticle.ukm.my/15571/1/26_ms0320_pdf_26801.pdf
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