| Summary: | Euphorbiaceae plants had been traditionally used in healing various diseases. This study was designed to determine the
secondary metabolites that exist in Malaysian Euphorbia milii (Euphorbiaceae) and it’s potential in antioxidant activities.
Dried leaves and flowers of E. milii were extracted using hexane, ethyl acetate, and methanol. The qualitative and quantitative
phytochemical analysis was performed toward the crude extracts. The outcomes showed that alkaloids, flavonoids, quinones,
carbohydrates, and reducing sugar were mainly present in all of the samples extracted by the three solvents. For quantitative
analysis, methanolic leaves extract contained the highest amount of flavonoids, given as 0.0867 ± 0.005 mg QE/g of the
sample compared to other extracts. Meanwhile, the determination of antioxidant activities of each extract showed that methanol
leaves extract consists of the highest antioxidant activity due to the presence of phytochemical compounds. This significant
data provides preliminary findings that may lead to further development as a potential source of herbal medicine.
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