Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
Syzygium filiforme var. filiforme is a plant variety from dicotyledonous plant family (Myrtaceae). Phytochemical studies on S. filiforme var. filiforme stem bark have successfully isolated and characterized arjunolic acid (1), alphitolic acid (2), betulinic acid (3), ursolic acid (4), ursolic acid 3...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Penerbit Universiti Kebangsaan Malaysia
2021
|
Online Access: | http://journalarticle.ukm.my/18295/1/7.pdf |
_version_ | 1796932817069801472 |
---|---|
author | Mohd Hafiz Ahmad, Norhazana Nor Izan, Nor Hadiani Ismail, Humera Naz, |
author_facet | Mohd Hafiz Ahmad, Norhazana Nor Izan, Nor Hadiani Ismail, Humera Naz, |
author_sort | Mohd Hafiz Ahmad, |
collection | UKM |
description | Syzygium filiforme var. filiforme is a plant variety from dicotyledonous plant family (Myrtaceae). Phytochemical studies on S. filiforme var. filiforme stem bark have successfully isolated and characterized arjunolic acid (1), alphitolic acid (2), betulinic acid (3), ursolic acid (4), ursolic acid 3-methyl ester (5), β-sitosterol (6) and stigmasterol (7). The inhibitory activities against free radical, starch, and bacteria for major compounds were tested by using DPPH, α-glucosidase and minimum inhibitory and bacterial concentration assays, respectively. No promising antioxidant activity was shown on tested samples except methanolic crude extract. For antidiabetic activity, methanolic and dichloromethane crude extracts displayed potent activity compared to 1-deoxynojirimycin. Minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) assays for antibacterial activity were evaluated on Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. All crude extracts and major compounds displayed weak and no promising activities for MIC method, respectively. Meanwhile, for MBC method, hexane crude extract and compound 1 showed inhibition against B. subtilis. |
first_indexed | 2024-03-06T04:38:09Z |
format | Article |
id | ukm.eprints-18295 |
institution | Universiti Kebangsaan Malaysia |
language | English |
last_indexed | 2024-03-06T04:38:09Z |
publishDate | 2021 |
publisher | Penerbit Universiti Kebangsaan Malaysia |
record_format | dspace |
spelling | ukm.eprints-182952022-04-06T05:59:33Z http://journalarticle.ukm.my/18295/ Phytochemicals and bioactivities of Syzygium filiforme var. filiforme Mohd Hafiz Ahmad, Norhazana Nor Izan, Nor Hadiani Ismail, Humera Naz, Syzygium filiforme var. filiforme is a plant variety from dicotyledonous plant family (Myrtaceae). Phytochemical studies on S. filiforme var. filiforme stem bark have successfully isolated and characterized arjunolic acid (1), alphitolic acid (2), betulinic acid (3), ursolic acid (4), ursolic acid 3-methyl ester (5), β-sitosterol (6) and stigmasterol (7). The inhibitory activities against free radical, starch, and bacteria for major compounds were tested by using DPPH, α-glucosidase and minimum inhibitory and bacterial concentration assays, respectively. No promising antioxidant activity was shown on tested samples except methanolic crude extract. For antidiabetic activity, methanolic and dichloromethane crude extracts displayed potent activity compared to 1-deoxynojirimycin. Minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) assays for antibacterial activity were evaluated on Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. All crude extracts and major compounds displayed weak and no promising activities for MIC method, respectively. Meanwhile, for MBC method, hexane crude extract and compound 1 showed inhibition against B. subtilis. Penerbit Universiti Kebangsaan Malaysia 2021-11 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18295/1/7.pdf Mohd Hafiz Ahmad, and Norhazana Nor Izan, and Nor Hadiani Ismail, and Humera Naz, (2021) Phytochemicals and bioactivities of Syzygium filiforme var. filiforme. Sains Malaysiana, 50 (11). pp. 3231-3239. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil11_2021/KandunganJilid50Bil11_2021.html |
spellingShingle | Mohd Hafiz Ahmad, Norhazana Nor Izan, Nor Hadiani Ismail, Humera Naz, Phytochemicals and bioactivities of Syzygium filiforme var. filiforme |
title | Phytochemicals and bioactivities of Syzygium filiforme var. filiforme |
title_full | Phytochemicals and bioactivities of Syzygium filiforme var. filiforme |
title_fullStr | Phytochemicals and bioactivities of Syzygium filiforme var. filiforme |
title_full_unstemmed | Phytochemicals and bioactivities of Syzygium filiforme var. filiforme |
title_short | Phytochemicals and bioactivities of Syzygium filiforme var. filiforme |
title_sort | phytochemicals and bioactivities of syzygium filiforme var filiforme |
url | http://journalarticle.ukm.my/18295/1/7.pdf |
work_keys_str_mv | AT mohdhafizahmad phytochemicalsandbioactivitiesofsyzygiumfiliformevarfiliforme AT norhazananorizan phytochemicalsandbioactivitiesofsyzygiumfiliformevarfiliforme AT norhadianiismail phytochemicalsandbioactivitiesofsyzygiumfiliformevarfiliforme AT humeranaz phytochemicalsandbioactivitiesofsyzygiumfiliformevarfiliforme |