Phytochemicals and bioactivities of Syzygium filiforme var. filiforme

Syzygium filiforme var. filiforme is a plant variety from dicotyledonous plant family (Myrtaceae). Phytochemical studies on S. filiforme var. filiforme stem bark have successfully isolated and characterized arjunolic acid (1), alphitolic acid (2), betulinic acid (3), ursolic acid (4), ursolic acid 3...

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Main Authors: Mohd Hafiz Ahmad, Norhazana Nor Izan, Nor Hadiani Ismail, Humera Naz
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/18295/1/7.pdf
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author Mohd Hafiz Ahmad,
Norhazana Nor Izan,
Nor Hadiani Ismail,
Humera Naz,
author_facet Mohd Hafiz Ahmad,
Norhazana Nor Izan,
Nor Hadiani Ismail,
Humera Naz,
author_sort Mohd Hafiz Ahmad,
collection UKM
description Syzygium filiforme var. filiforme is a plant variety from dicotyledonous plant family (Myrtaceae). Phytochemical studies on S. filiforme var. filiforme stem bark have successfully isolated and characterized arjunolic acid (1), alphitolic acid (2), betulinic acid (3), ursolic acid (4), ursolic acid 3-methyl ester (5), β-sitosterol (6) and stigmasterol (7). The inhibitory activities against free radical, starch, and bacteria for major compounds were tested by using DPPH, α-glucosidase and minimum inhibitory and bacterial concentration assays, respectively. No promising antioxidant activity was shown on tested samples except methanolic crude extract. For antidiabetic activity, methanolic and dichloromethane crude extracts displayed potent activity compared to 1-deoxynojirimycin. Minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) assays for antibacterial activity were evaluated on Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. All crude extracts and major compounds displayed weak and no promising activities for MIC method, respectively. Meanwhile, for MBC method, hexane crude extract and compound 1 showed inhibition against B. subtilis.
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spelling ukm.eprints-182952022-04-06T05:59:33Z http://journalarticle.ukm.my/18295/ Phytochemicals and bioactivities of Syzygium filiforme var. filiforme Mohd Hafiz Ahmad, Norhazana Nor Izan, Nor Hadiani Ismail, Humera Naz, Syzygium filiforme var. filiforme is a plant variety from dicotyledonous plant family (Myrtaceae). Phytochemical studies on S. filiforme var. filiforme stem bark have successfully isolated and characterized arjunolic acid (1), alphitolic acid (2), betulinic acid (3), ursolic acid (4), ursolic acid 3-methyl ester (5), β-sitosterol (6) and stigmasterol (7). The inhibitory activities against free radical, starch, and bacteria for major compounds were tested by using DPPH, α-glucosidase and minimum inhibitory and bacterial concentration assays, respectively. No promising antioxidant activity was shown on tested samples except methanolic crude extract. For antidiabetic activity, methanolic and dichloromethane crude extracts displayed potent activity compared to 1-deoxynojirimycin. Minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) assays for antibacterial activity were evaluated on Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. All crude extracts and major compounds displayed weak and no promising activities for MIC method, respectively. Meanwhile, for MBC method, hexane crude extract and compound 1 showed inhibition against B. subtilis. Penerbit Universiti Kebangsaan Malaysia 2021-11 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18295/1/7.pdf Mohd Hafiz Ahmad, and Norhazana Nor Izan, and Nor Hadiani Ismail, and Humera Naz, (2021) Phytochemicals and bioactivities of Syzygium filiforme var. filiforme. Sains Malaysiana, 50 (11). pp. 3231-3239. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil11_2021/KandunganJilid50Bil11_2021.html
spellingShingle Mohd Hafiz Ahmad,
Norhazana Nor Izan,
Nor Hadiani Ismail,
Humera Naz,
Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
title Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
title_full Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
title_fullStr Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
title_full_unstemmed Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
title_short Phytochemicals and bioactivities of Syzygium filiforme var. filiforme
title_sort phytochemicals and bioactivities of syzygium filiforme var filiforme
url http://journalarticle.ukm.my/18295/1/7.pdf
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