The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.)
Dimefluthrin, a synthetic pyrethroid insecticide, claims to be safe and harmless to mammals. However, the potential risk of mosquito coils containing dimefluthrin to pregnant mice remains uncertain. This study aimed to examine the teratogenic effect of dimefluthrin when inhaled by pregnant mice at d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/23568/1/MJ%207.pdf |
| _version_ | 1811136818642419712 |
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| author | Efrizal, Ikbal, Chika Afrilia Jannatan, Robby |
| author_facet | Efrizal, Ikbal, Chika Afrilia Jannatan, Robby |
| author_sort | Efrizal, |
| collection | UKM |
| description | Dimefluthrin, a synthetic pyrethroid insecticide, claims to be safe and harmless to mammals. However, the potential risk of mosquito coils containing dimefluthrin to pregnant mice remains uncertain. This study aimed to examine the teratogenic effect of dimefluthrin when inhaled by pregnant mice at different stages of gestation. The study used mosquito coils with 0.031% dimefluthrin as the active ingredient and was exposed to pregnant mice at various pregnancy stages. The results revealed that mosquito coils with dimefluthrin had teratogenic effects, reducing the number of live fetuses and increasing the number of dead fetuses, especially from the seventh to the eighteenth day of pregnancy. Additionally, there was a decrease in fetal weight, length, and volume, particularly during the seventh to eighth day of gestation. Hemorrhages were observed as fetal abnormalities and were highest three hr after exposure every day during pregnancy. The conclusion of this research is pregnant mice exposed to mosquito coil smoke containing dimefluthrin experienced a decrease in the number of live fetuses and an increase in fetal mortality. While there was no significant impact on reabsorption, the fetuses showed reduced weight, and size, and an increased incidence of hemorrhages when exposed for three hr daily during pregnancy. |
| first_indexed | 2024-09-24T01:26:23Z |
| format | Article |
| id | ukm.eprints-23568 |
| institution | Universiti Kebangsaan Malaysia |
| language | English |
| last_indexed | 2024-09-24T01:26:23Z |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | dspace |
| spelling | ukm.eprints-235682024-05-17T03:42:08Z http://journalarticle.ukm.my/23568/ The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) Efrizal, Ikbal, Chika Afrilia Jannatan, Robby Dimefluthrin, a synthetic pyrethroid insecticide, claims to be safe and harmless to mammals. However, the potential risk of mosquito coils containing dimefluthrin to pregnant mice remains uncertain. This study aimed to examine the teratogenic effect of dimefluthrin when inhaled by pregnant mice at different stages of gestation. The study used mosquito coils with 0.031% dimefluthrin as the active ingredient and was exposed to pregnant mice at various pregnancy stages. The results revealed that mosquito coils with dimefluthrin had teratogenic effects, reducing the number of live fetuses and increasing the number of dead fetuses, especially from the seventh to the eighteenth day of pregnancy. Additionally, there was a decrease in fetal weight, length, and volume, particularly during the seventh to eighth day of gestation. Hemorrhages were observed as fetal abnormalities and were highest three hr after exposure every day during pregnancy. The conclusion of this research is pregnant mice exposed to mosquito coil smoke containing dimefluthrin experienced a decrease in the number of live fetuses and an increase in fetal mortality. While there was no significant impact on reabsorption, the fetuses showed reduced weight, and size, and an increased incidence of hemorrhages when exposed for three hr daily during pregnancy. Penerbit Universiti Kebangsaan Malaysia 2024 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/23568/1/MJ%207.pdf Efrizal, and Ikbal, Chika Afrilia and Jannatan, Robby (2024) The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.). Malaysian Applied Biology, 53 (1). pp. 85-91. ISSN 0126-8643 https://jms.mabjournal.com/index.php/mab/issue/view/58 |
| spellingShingle | Efrizal, Ikbal, Chika Afrilia Jannatan, Robby The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) |
| title | The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) |
| title_full | The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) |
| title_fullStr | The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) |
| title_full_unstemmed | The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) |
| title_short | The teratogenic effect of dimefluthrin-based mosquito coils on pregnant mice (Mus musculus L.) |
| title_sort | teratogenic effect of dimefluthrin based mosquito coils on pregnant mice mus musculus l |
| url | http://journalarticle.ukm.my/23568/1/MJ%207.pdf |
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