Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma
The most common cause of permanent vision loss or blindness in the world is glaucoma. Primary Open Angle Glaucoma (POAG) develops when the eye drainage canals clog over time, increasing intraocular pressure and damaging the optic nerve. In POAG, an ophthalmology examination usually shows an open ant...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/24497/1/SS%2015.pdf |
| _version_ | 1817926845215014912 |
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| author | Sucijanti, Yuan, Zhi Lan Liang, Ya Hong, Sun Gu, Liu Wei Zhenli, Si |
| author_facet | Sucijanti, Yuan, Zhi Lan Liang, Ya Hong, Sun Gu, Liu Wei Zhenli, Si |
| author_sort | Sucijanti, |
| collection | UKM |
| description | The most common cause of permanent vision loss or blindness in the world is glaucoma. Primary Open Angle Glaucoma (POAG) develops when the eye drainage canals clog over time, increasing intraocular pressure and damaging the optic nerve. In POAG, an ophthalmology examination usually shows an open anterior chamber and chronic, irreversible multifactorial optic neuropathy followed by central visual field loss. OCT is specifically employed to investigate the elasticity of tissue, particularly in Schlemm’s canal. This study aims to analyzed the morphological parameters of Schlemm’s canal among patients with POAG and normal healthy control. In this observational study, we included one hundred patients, among them 50 patients had POAG, and 50 healthy controls, and both eyes were assessed. We measured the study cohort’s and the healthy cohort’s eyes’ elevated IOP and the Schlemm’s canal cross-sectional area (CSA). RT-Vue OCT was used to analyze both eyes’ temporal, superior, inferior, and nasal regions. The data were analyzed using both univariate and bivariate methods. The characteristics of the morphological measurement of Schlemm’s canal results were similar to those of Kagemann et al. There was a significant difference between age and SC measurement, but no correlation was observed between SC measurement and IOP or visual acuity. OCT is a useful way to evaluate the morphological status of Schlemm Canal in glaucoma patients. The eyes with POAG had smaller Schlemm’s Canal- CSA than the normal eyes. The Schlemm canal-CSA in Chinese people had no differences from that of peoples of other races. |
| first_indexed | 2024-12-09T02:09:01Z |
| format | Article |
| id | ukm.eprints-24497 |
| institution | Universiti Kebangsaan Malaysia |
| language | English |
| last_indexed | 2024-12-09T02:09:01Z |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
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| spelling | ukm.eprints-244972024-11-12T04:58:46Z http://journalarticle.ukm.my/24497/ Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma Sucijanti, Yuan, Zhi Lan Liang, Ya Hong, Sun Gu, Liu Wei Zhenli, Si The most common cause of permanent vision loss or blindness in the world is glaucoma. Primary Open Angle Glaucoma (POAG) develops when the eye drainage canals clog over time, increasing intraocular pressure and damaging the optic nerve. In POAG, an ophthalmology examination usually shows an open anterior chamber and chronic, irreversible multifactorial optic neuropathy followed by central visual field loss. OCT is specifically employed to investigate the elasticity of tissue, particularly in Schlemm’s canal. This study aims to analyzed the morphological parameters of Schlemm’s canal among patients with POAG and normal healthy control. In this observational study, we included one hundred patients, among them 50 patients had POAG, and 50 healthy controls, and both eyes were assessed. We measured the study cohort’s and the healthy cohort’s eyes’ elevated IOP and the Schlemm’s canal cross-sectional area (CSA). RT-Vue OCT was used to analyze both eyes’ temporal, superior, inferior, and nasal regions. The data were analyzed using both univariate and bivariate methods. The characteristics of the morphological measurement of Schlemm’s canal results were similar to those of Kagemann et al. There was a significant difference between age and SC measurement, but no correlation was observed between SC measurement and IOP or visual acuity. OCT is a useful way to evaluate the morphological status of Schlemm Canal in glaucoma patients. The eyes with POAG had smaller Schlemm’s Canal- CSA than the normal eyes. The Schlemm canal-CSA in Chinese people had no differences from that of peoples of other races. Penerbit Universiti Kebangsaan Malaysia 2024 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/24497/1/SS%2015.pdf Sucijanti, and Yuan, Zhi Lan and Liang, Ya and Hong, Sun and Gu, Liu Wei and Zhenli, Si (2024) Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma. Sains Malaysiana, 53 (9). pp. 3097-3111. ISSN 0126-6039 https://www.ukm.my/jsm/english_journals/vol53num9_2024/contentsVol53num9_2024.html |
| spellingShingle | Sucijanti, Yuan, Zhi Lan Liang, Ya Hong, Sun Gu, Liu Wei Zhenli, Si Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma |
| title | Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma |
| title_full | Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma |
| title_fullStr | Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma |
| title_full_unstemmed | Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma |
| title_short | Analysis of Schlemm’s canal measurement and evaluation with fourier-domain optical coherence tomography in Primary Open-Angle Glaucoma |
| title_sort | analysis of schlemm s canal measurement and evaluation with fourier domain optical coherence tomography in primary open angle glaucoma |
| url | http://journalarticle.ukm.my/24497/1/SS%2015.pdf |
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