Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity
The increasing prevalence of microbial infections and antibiotic resistance has sparked interest in investigating the therapeutic potential of silver nanoparticles (AgNPs) as effective antimicrobial agents. The current study seeks to optimize the synthesis of AgNPs using Chrysanthemum morifolium (CM...
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/24748/1/MAE%201.pdf |
| _version_ | 1824449806220656640 |
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| author | Lai, Mun Leong Ghim, Hock Ong Khye, Er Loh |
| author_facet | Lai, Mun Leong Ghim, Hock Ong Khye, Er Loh |
| author_sort | Lai, Mun Leong |
| collection | UKM |
| description | The increasing prevalence of microbial infections and antibiotic resistance has sparked interest in investigating the therapeutic potential of silver nanoparticles (AgNPs) as effective antimicrobial agents. The current study seeks to optimize the synthesis of AgNPs using Chrysanthemum morifolium (CM) extract and evaluate their antibacterial activity. Maximum synthesis of CM-AgNPs was achieved using 10 mM of AgNO3 and 20 mg/mL of CM extract at a 6:4 ratio and 3 hr of incubation period at pH 11 and 40°C. The Chrysanthemum morifolium-synthesized silver nanoparticles (CM-AgNPs) displayed a spherical shape, with sizes ranging from 12 to 34 nm. The minimum inhibitory concentration (MIC) against Pseudomonas mirabilis, Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae were 0.0117, 0.0117, 0.0031, and 0.100 mg/mL, respectively. CM-AgNPs demonstrated notable antibiofilm activity of 49.26%, 87.31%, and 66.23% against P. mirabilis, S. aureus, and K. pneumoniae, respectively. These results indicate that CM-AgNPs possess antibacterial properties and hold promise as antimicrobial agents. |
| first_indexed | 2025-02-19T02:08:41Z |
| format | Article |
| id | ukm.eprints-24748 |
| institution | Universiti Kebangsaan Malaysia |
| language | English |
| last_indexed | 2025-02-19T02:08:41Z |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | dspace |
| spelling | ukm.eprints-247482025-01-23T04:12:32Z http://journalarticle.ukm.my/24748/ Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity Lai, Mun Leong Ghim, Hock Ong Khye, Er Loh The increasing prevalence of microbial infections and antibiotic resistance has sparked interest in investigating the therapeutic potential of silver nanoparticles (AgNPs) as effective antimicrobial agents. The current study seeks to optimize the synthesis of AgNPs using Chrysanthemum morifolium (CM) extract and evaluate their antibacterial activity. Maximum synthesis of CM-AgNPs was achieved using 10 mM of AgNO3 and 20 mg/mL of CM extract at a 6:4 ratio and 3 hr of incubation period at pH 11 and 40°C. The Chrysanthemum morifolium-synthesized silver nanoparticles (CM-AgNPs) displayed a spherical shape, with sizes ranging from 12 to 34 nm. The minimum inhibitory concentration (MIC) against Pseudomonas mirabilis, Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae were 0.0117, 0.0117, 0.0031, and 0.100 mg/mL, respectively. CM-AgNPs demonstrated notable antibiofilm activity of 49.26%, 87.31%, and 66.23% against P. mirabilis, S. aureus, and K. pneumoniae, respectively. These results indicate that CM-AgNPs possess antibacterial properties and hold promise as antimicrobial agents. Penerbit Universiti Kebangsaan Malaysia 2024 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/24748/1/MAE%201.pdf Lai, Mun Leong and Ghim, Hock Ong and Khye, Er Loh (2024) Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity. Malaysian Applied Biology, 53 (4). pp. 1-6. ISSN 0126-8643 https://jms.mabjournal.com/index.php/mab/issue/view/63 |
| spellingShingle | Lai, Mun Leong Ghim, Hock Ong Khye, Er Loh Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| title | Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| title_full | Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| title_fullStr | Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| title_full_unstemmed | Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| title_short | Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| title_sort | green synthesis of chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity |
| url | http://journalarticle.ukm.my/24748/1/MAE%201.pdf |
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