Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.

A prospective randomised controlled trial was conducted at a tertiary medical center on 154 patients for the treatment of spontaneous first trimester incomplete miscarriage. The intervention group (n=77) received out-patient administration of misoprostol whereas the control group (n=77) received in-...

Full description

Bibliographic Details
Main Authors: Annamalai, Lim, Pei Shan, Nur Azurah AG, Aqmar Suraya Sulaiman, Syed Zulkifli Syed Zakaria, uhammad Abdul Jamil Mohd. Yassin, M
Format: Article
Language:English
Published: Department of Surgery, UKM Medical Centre 2014
Online Access:http://journalarticle.ukm.my/7732/1/86.pdf
_version_ 1796930610887917568
author Annamalai,
Lim, Pei Shan
Nur Azurah AG,
Aqmar Suraya Sulaiman,
Syed Zulkifli Syed Zakaria,
uhammad Abdul Jamil Mohd. Yassin, M
author_facet Annamalai,
Lim, Pei Shan
Nur Azurah AG,
Aqmar Suraya Sulaiman,
Syed Zulkifli Syed Zakaria,
uhammad Abdul Jamil Mohd. Yassin, M
author_sort Annamalai,
collection UKM
description A prospective randomised controlled trial was conducted at a tertiary medical center on 154 patients for the treatment of spontaneous first trimester incomplete miscarriage. The intervention group (n=77) received out-patient administration of misoprostol whereas the control group (n=77) received in-patient administration of misoprostol. The intravaginal misoprostol dosage administered was 800mcg 8 hourly to maximum of 3 doses. They were reassessed at Day 7. The primary outcome evaluated were success of evacuation, side effects, cost and patient acceptability. The secondary outcomes evaluated were mean reduction of endometrial thickness, days of passing out POC, duration of bleeding and mean reduction in hemoglobin. Assessment for treatment failure was done at day 7. Surgical evacuation was then offered.
first_indexed 2024-03-06T04:05:38Z
format Article
id ukm.eprints-7732
institution Universiti Kebangsaan Malaysia
language English
last_indexed 2024-03-06T04:05:38Z
publishDate 2014
publisher Department of Surgery, UKM Medical Centre
record_format dspace
spelling ukm.eprints-77322016-12-14T06:45:01Z http://journalarticle.ukm.my/7732/ Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial. Annamalai, Lim, Pei Shan Nur Azurah AG, Aqmar Suraya Sulaiman, Syed Zulkifli Syed Zakaria, uhammad Abdul Jamil Mohd. Yassin, M A prospective randomised controlled trial was conducted at a tertiary medical center on 154 patients for the treatment of spontaneous first trimester incomplete miscarriage. The intervention group (n=77) received out-patient administration of misoprostol whereas the control group (n=77) received in-patient administration of misoprostol. The intravaginal misoprostol dosage administered was 800mcg 8 hourly to maximum of 3 doses. They were reassessed at Day 7. The primary outcome evaluated were success of evacuation, side effects, cost and patient acceptability. The secondary outcomes evaluated were mean reduction of endometrial thickness, days of passing out POC, duration of bleeding and mean reduction in hemoglobin. Assessment for treatment failure was done at day 7. Surgical evacuation was then offered. Department of Surgery, UKM Medical Centre 2014-01-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/7732/1/86.pdf Annamalai, and Lim, Pei Shan and Nur Azurah AG, and Aqmar Suraya Sulaiman, and Syed Zulkifli Syed Zakaria, and uhammad Abdul Jamil Mohd. Yassin, M (2014) Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial. Journal of Surgical Academia, 4 (1). p. 86. ISSN 2231-7481 http://jsurgacad.com/
spellingShingle Annamalai,
Lim, Pei Shan
Nur Azurah AG,
Aqmar Suraya Sulaiman,
Syed Zulkifli Syed Zakaria,
uhammad Abdul Jamil Mohd. Yassin, M
Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.
title Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.
title_full Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.
title_fullStr Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.
title_full_unstemmed Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.
title_short Out-patient intravaginal misoprostol versus in-patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in UKMMC: a randomised controlled trial.
title_sort out patient intravaginal misoprostol versus in patient intravaginal misoprostol for the treatment of first trimester incomplete miscarriage in ukmmc a randomised controlled trial
url http://journalarticle.ukm.my/7732/1/86.pdf
work_keys_str_mv AT annamalai outpatientintravaginalmisoprostolversusinpatientintravaginalmisoprostolforthetreatmentoffirsttrimesterincompletemiscarriageinukmmcarandomisedcontrolledtrial
AT limpeishan outpatientintravaginalmisoprostolversusinpatientintravaginalmisoprostolforthetreatmentoffirsttrimesterincompletemiscarriageinukmmcarandomisedcontrolledtrial
AT nurazurahag outpatientintravaginalmisoprostolversusinpatientintravaginalmisoprostolforthetreatmentoffirsttrimesterincompletemiscarriageinukmmcarandomisedcontrolledtrial
AT aqmarsurayasulaiman outpatientintravaginalmisoprostolversusinpatientintravaginalmisoprostolforthetreatmentoffirsttrimesterincompletemiscarriageinukmmcarandomisedcontrolledtrial
AT syedzulkiflisyedzakaria outpatientintravaginalmisoprostolversusinpatientintravaginalmisoprostolforthetreatmentoffirsttrimesterincompletemiscarriageinukmmcarandomisedcontrolledtrial
AT uhammadabduljamilmohdyassinm outpatientintravaginalmisoprostolversusinpatientintravaginalmisoprostolforthetreatmentoffirsttrimesterincompletemiscarriageinukmmcarandomisedcontrolledtrial