Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis

We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopat...

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Main Authors: Lee, CL, Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang, Md. Isa N, Nor Azlin Mohamed Ismail
Format: Article
Language:English
Published: Faculty of Medicine, UKM Medical Centre 2016
Online Access:http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf
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author Lee, CL
Aini Amelia Zainuddin,
Abdul Kadir Abdul Karim,
Yulianty Arifuddin,
Law, Zhee Kang
Md. Isa N,
Nor Azlin Mohamed Ismail,
author_facet Lee, CL
Aini Amelia Zainuddin,
Abdul Kadir Abdul Karim,
Yulianty Arifuddin,
Law, Zhee Kang
Md. Isa N,
Nor Azlin Mohamed Ismail,
author_sort Lee, CL
collection UKM
description We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery.
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spelling ukm.eprints-98412016-12-14T06:51:00Z http://journalarticle.ukm.my/9841/ Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. Faculty of Medicine, UKM Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf Lee, CL and Aini Amelia Zainuddin, and Abdul Kadir Abdul Karim, and Yulianty Arifuddin, and Law, Zhee Kang and Md. Isa N, and Nor Azlin Mohamed Ismail, (2016) Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis. Journal of Surgical Academia, 6 (1). pp. 66-69. ISSN 2231-7481 http://jsurgacad.com/toc/6/1
spellingShingle Lee, CL
Aini Amelia Zainuddin,
Abdul Kadir Abdul Karim,
Yulianty Arifuddin,
Law, Zhee Kang
Md. Isa N,
Nor Azlin Mohamed Ismail,
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_full Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_fullStr Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_full_unstemmed Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_short Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_sort anti n methyl d aspartate receptor encephalitis with ovarian teratoma a dilemma in diagnosis
url http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf
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