Transforming growth factor-ß enhances invasion and metastasis in Ras-transfected human malignant epidermal keratinocytes
Transforming growth factor-ß (TGF-ß) is known to act as a tumour suppressor early in carcinogenesis, but then switches to a pro-metastatic factor in some late stage cancers. However, the actions of TGF-ß are context dependent, and it is currently unclear how TGF-ß influences the progression of human...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Blackwell Publishing
2012
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/10107/1/Transforming_growth_factor-b_enhances_invasion_and_metastasis.pdf |