Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley
The rhizomes of Alpinia pahangensis Ridley yielded a new bis-labdanic diterpene for which the name pahangensin A (1) was proposed along with a new labdane diterpene, pahangensin B (2). Their structures were elucidated by spectroscopic methods including, 1D and 2D NMR techniques and LCMS-IT-TOF anal...
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| Format: | Article |
| Language: | English |
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Elsevier
2013
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| Online Access: | http://eprints.um.edu.my/10109/1/Pahangensin_A_and_B%2C_two_new_antibacterial_diterpenes.pdf |
| _version_ | 1825719809816395776 |
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| author | Sivasothy, Y. Ibrahim, H. Paliany, A.S. Alias, S.A. Awang, Khalijah |
| author_facet | Sivasothy, Y. Ibrahim, H. Paliany, A.S. Alias, S.A. Awang, Khalijah |
| author_sort | Sivasothy, Y. |
| collection | UM |
| description | The rhizomes of Alpinia pahangensis Ridley yielded a new bis-labdanic diterpene for which the name pahangensin A (1) was proposed along with a new labdane diterpene, pahangensin B (2). Their structures were elucidated by spectroscopic methods including, 1D and 2D NMR techniques and LCMS-IT-TOF
analysis. Pahangensin A (1) was found to be an antibacterial agent against Staphylococcus aureus, Bacillus cereus and Bacillus subtilis with MIC values less than 100 lg/mL, respectively. Pahangensin B (2) exhibited antibacterial activity (MIC <100 lg/mL) against B. cereus. |
| first_indexed | 2024-03-06T05:25:26Z |
| format | Article |
| id | um.eprints-10109 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:25:26Z |
| publishDate | 2013 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-101092019-03-01T09:18:44Z http://eprints.um.edu.my/10109/ Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley Sivasothy, Y. Ibrahim, H. Paliany, A.S. Alias, S.A. Awang, Khalijah Q Science (General) The rhizomes of Alpinia pahangensis Ridley yielded a new bis-labdanic diterpene for which the name pahangensin A (1) was proposed along with a new labdane diterpene, pahangensin B (2). Their structures were elucidated by spectroscopic methods including, 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Pahangensin A (1) was found to be an antibacterial agent against Staphylococcus aureus, Bacillus cereus and Bacillus subtilis with MIC values less than 100 lg/mL, respectively. Pahangensin B (2) exhibited antibacterial activity (MIC <100 lg/mL) against B. cereus. Elsevier 2013 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10109/1/Pahangensin_A_and_B%2C_two_new_antibacterial_diterpenes.pdf Sivasothy, Y. and Ibrahim, H. and Paliany, A.S. and Alias, S.A. and Awang, Khalijah (2013) Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. Bioorganic and Medicinal Chemistry Letters, 23. pp. 6280-6285. ISSN 0960-894X, |
| spellingShingle | Q Science (General) Sivasothy, Y. Ibrahim, H. Paliany, A.S. Alias, S.A. Awang, Khalijah Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley |
| title | Pahangensin A and B, two new antibacterial diterpenes
from the rhizomes of Alpinia pahangensis Ridley |
| title_full | Pahangensin A and B, two new antibacterial diterpenes
from the rhizomes of Alpinia pahangensis Ridley |
| title_fullStr | Pahangensin A and B, two new antibacterial diterpenes
from the rhizomes of Alpinia pahangensis Ridley |
| title_full_unstemmed | Pahangensin A and B, two new antibacterial diterpenes
from the rhizomes of Alpinia pahangensis Ridley |
| title_short | Pahangensin A and B, two new antibacterial diterpenes
from the rhizomes of Alpinia pahangensis Ridley |
| title_sort | pahangensin a and b two new antibacterial diterpenes from the rhizomes of alpinia pahangensis ridley |
| topic | Q Science (General) |
| url | http://eprints.um.edu.my/10109/1/Pahangensin_A_and_B%2C_two_new_antibacterial_diterpenes.pdf |
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