Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia

The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone...

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Main Authors: Karunakaran, R., Sun, T.T., Rahim, F.F., Bee, B.L., Sam, I.C., Kahar-Bador, M., Hassan, H., Puthucheary, S.D.
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:http://eprints.um.edu.my/10170/1/Ceftriaxone_Resistance_and_Genes_Encoding_Extended-Spectrum.pdf
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author Karunakaran, R.
Sun, T.T.
Rahim, F.F.
Bee, B.L.
Sam, I.C.
Kahar-Bador, M.
Hassan, H.
Puthucheary, S.D.
author_facet Karunakaran, R.
Sun, T.T.
Rahim, F.F.
Bee, B.L.
Sam, I.C.
Kahar-Bador, M.
Hassan, H.
Puthucheary, S.D.
author_sort Karunakaran, R.
collection UM
description The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone was 2.7z (2/74) in 2008, 4.0z (3/75) in 2009, and 3.4z (5/149) overall. CTX-M ESBL genes were detected in 2 of the 5 ceftriaxone-resistant isolates. The prevalence of ceftriaxone resistance, although low, is a concern because it limits therapeutic options. Continued surveillance of ceftriaxone resistance is important to monitor its trends
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spelling um.eprints-101702014-10-23T08:30:35Z http://eprints.um.edu.my/10170/ Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia Karunakaran, R. Sun, T.T. Rahim, F.F. Bee, B.L. Sam, I.C. Kahar-Bador, M. Hassan, H. Puthucheary, S.D. R Medicine (General) The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone was 2.7z (2/74) in 2008, 4.0z (3/75) in 2009, and 3.4z (5/149) overall. CTX-M ESBL genes were detected in 2 of the 5 ceftriaxone-resistant isolates. The prevalence of ceftriaxone resistance, although low, is a concern because it limits therapeutic options. Continued surveillance of ceftriaxone resistance is important to monitor its trends 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10170/1/Ceftriaxone_Resistance_and_Genes_Encoding_Extended-Spectrum.pdf Karunakaran, R. and Sun, T.T. and Rahim, F.F. and Bee, B.L. and Sam, I.C. and Kahar-Bador, M. and Hassan, H. and Puthucheary, S.D. (2012) Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia. Japanese Journal of Infectious Diseases, 65. ISSN 1344-6304,
spellingShingle R Medicine (General)
Karunakaran, R.
Sun, T.T.
Rahim, F.F.
Bee, B.L.
Sam, I.C.
Kahar-Bador, M.
Hassan, H.
Puthucheary, S.D.
Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
title Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
title_full Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
title_fullStr Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
title_full_unstemmed Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
title_short Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
title_sort ceftriaxone resistance and genes encoding extended spectrum ss lactamase among non typhoidal salmonella species from a tertiary care hospital in kuala lumpur malaysia
topic R Medicine (General)
url http://eprints.um.edu.my/10170/1/Ceftriaxone_Resistance_and_Genes_Encoding_Extended-Spectrum.pdf
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