Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia
The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone...
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Format: | Article |
Language: | English |
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2012
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Online Access: | http://eprints.um.edu.my/10170/1/Ceftriaxone_Resistance_and_Genes_Encoding_Extended-Spectrum.pdf |
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author | Karunakaran, R. Sun, T.T. Rahim, F.F. Bee, B.L. Sam, I.C. Kahar-Bador, M. Hassan, H. Puthucheary, S.D. |
author_facet | Karunakaran, R. Sun, T.T. Rahim, F.F. Bee, B.L. Sam, I.C. Kahar-Bador, M. Hassan, H. Puthucheary, S.D. |
author_sort | Karunakaran, R. |
collection | UM |
description | The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to
ceftriaxone was 2.7z (2/74) in 2008, 4.0z (3/75) in 2009, and 3.4z (5/149) overall. CTX-M ESBL genes were detected in 2 of the 5 ceftriaxone-resistant isolates. The prevalence of ceftriaxone resistance, although low, is a concern because it limits therapeutic options. Continued surveillance of ceftriaxone resistance is important to monitor its trends |
first_indexed | 2024-03-06T05:25:34Z |
format | Article |
id | um.eprints-10170 |
institution | Universiti Malaya |
language | English |
last_indexed | 2024-03-06T05:25:34Z |
publishDate | 2012 |
record_format | dspace |
spelling | um.eprints-101702014-10-23T08:30:35Z http://eprints.um.edu.my/10170/ Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia Karunakaran, R. Sun, T.T. Rahim, F.F. Bee, B.L. Sam, I.C. Kahar-Bador, M. Hassan, H. Puthucheary, S.D. R Medicine (General) The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone was 2.7z (2/74) in 2008, 4.0z (3/75) in 2009, and 3.4z (5/149) overall. CTX-M ESBL genes were detected in 2 of the 5 ceftriaxone-resistant isolates. The prevalence of ceftriaxone resistance, although low, is a concern because it limits therapeutic options. Continued surveillance of ceftriaxone resistance is important to monitor its trends 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10170/1/Ceftriaxone_Resistance_and_Genes_Encoding_Extended-Spectrum.pdf Karunakaran, R. and Sun, T.T. and Rahim, F.F. and Bee, B.L. and Sam, I.C. and Kahar-Bador, M. and Hassan, H. and Puthucheary, S.D. (2012) Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia. Japanese Journal of Infectious Diseases, 65. ISSN 1344-6304, |
spellingShingle | R Medicine (General) Karunakaran, R. Sun, T.T. Rahim, F.F. Bee, B.L. Sam, I.C. Kahar-Bador, M. Hassan, H. Puthucheary, S.D. Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia |
title | Ceftriaxone resistance and genes encoding extended-spectrum
ß-lactamase among non-typhoidal salmonella species from
a tertiary care hospital in Kuala Lumpur, Malaysia |
title_full | Ceftriaxone resistance and genes encoding extended-spectrum
ß-lactamase among non-typhoidal salmonella species from
a tertiary care hospital in Kuala Lumpur, Malaysia |
title_fullStr | Ceftriaxone resistance and genes encoding extended-spectrum
ß-lactamase among non-typhoidal salmonella species from
a tertiary care hospital in Kuala Lumpur, Malaysia |
title_full_unstemmed | Ceftriaxone resistance and genes encoding extended-spectrum
ß-lactamase among non-typhoidal salmonella species from
a tertiary care hospital in Kuala Lumpur, Malaysia |
title_short | Ceftriaxone resistance and genes encoding extended-spectrum
ß-lactamase among non-typhoidal salmonella species from
a tertiary care hospital in Kuala Lumpur, Malaysia |
title_sort | ceftriaxone resistance and genes encoding extended spectrum ss lactamase among non typhoidal salmonella species from a tertiary care hospital in kuala lumpur malaysia |
topic | R Medicine (General) |
url | http://eprints.um.edu.my/10170/1/Ceftriaxone_Resistance_and_Genes_Encoding_Extended-Spectrum.pdf |
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