Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR...
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Format: | Article |
Language: | English |
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Elsevier
2010
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Online Access: | http://eprints.um.edu.my/10406/1/Aspidospermatan%E2%80%93aspidospermatan_and_eburnane-sarpagine_bisindole_alkaloids_from_Leuconotis.pdf |
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author | Kam, Toh Seok Gan, C.Y. Low, Y.Y. Robinson, W.T. Komiyama, K. |
author_facet | Kam, Toh Seok Gan, C.Y. Low, Y.Y. Robinson, W.T. Komiyama, K. |
author_sort | Kam, Toh Seok |
collection | UM |
description | Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed
weak cytotoxicity towards human KB cells. |
first_indexed | 2024-03-06T05:26:04Z |
format | Article |
id | um.eprints-10406 |
institution | Universiti Malaya |
language | English |
last_indexed | 2024-03-06T05:26:04Z |
publishDate | 2010 |
publisher | Elsevier |
record_format | dspace |
spelling | um.eprints-104062021-03-22T03:38:13Z http://eprints.um.edu.my/10406/ Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis Kam, Toh Seok Gan, C.Y. Low, Y.Y. Robinson, W.T. Komiyama, K. QD Chemistry Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells. Elsevier 2010 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10406/1/Aspidospermatan%E2%80%93aspidospermatan_and_eburnane-sarpagine_bisindole_alkaloids_from_Leuconotis.pdf Kam, Toh Seok and Gan, C.Y. and Low, Y.Y. and Robinson, W.T. and Komiyama, K. (2010) Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis. Phytochemistry, 71. pp. 1365-1370. ISSN 0031-9422, DOI https://doi.org/10.1016/j.phytochem.2010.05.015 <https://doi.org/10.1016/j.phytochem.2010.05.015>. doi:10.1016/j.phytochem.2010.05.015 |
spellingShingle | QD Chemistry Kam, Toh Seok Gan, C.Y. Low, Y.Y. Robinson, W.T. Komiyama, K. Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
title | Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
title_full | Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
title_fullStr | Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
title_full_unstemmed | Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
title_short | Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis |
title_sort | aspidospermatan aspidospermatan and eburnane sarpagine bisindole alkaloids from leuconotis |
topic | QD Chemistry |
url | http://eprints.um.edu.my/10406/1/Aspidospermatan%E2%80%93aspidospermatan_and_eburnane-sarpagine_bisindole_alkaloids_from_Leuconotis.pdf |
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