Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms

Chitin oligosaccharides (COSs) can be isolated from various natural resources, which have widely been used in biological active supplements (BAS) for the benefit of humankind. Several technological approaches for the preparation of COSs such as enzymatic, chemical, acid-catalysts hydrolysis, microwa...

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Main Authors: Ahmed, A.B.A., Taha, R.M., Mohajer, S., Elaagib, M.E., Kim, S.K.
Format: Article
Published: 2012
Subjects:
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author Ahmed, A.B.A.
Taha, R.M.
Mohajer, S.
Elaagib, M.E.
Kim, S.K.
author_facet Ahmed, A.B.A.
Taha, R.M.
Mohajer, S.
Elaagib, M.E.
Kim, S.K.
author_sort Ahmed, A.B.A.
collection UM
description Chitin oligosaccharides (COSs) can be isolated from various natural resources, which have widely been used in biological active supplements (BAS) for the benefit of humankind. Several technological approaches for the preparation of COSs such as enzymatic, chemical, acid-catalysts hydrolysis, microwave radiation, membrane bioreactor methods have been developed and among them, membrane bioreactor, bioconversion and continuous mass production technologies are reported to be excellent. Compounds isolated from natural products have made a drastic impact on the pharmaceutical industry and especially, water-soluble chitin oligosaccharides have shown greater clinical activity, which have been demonstrated in various cell lines of disease significance. The activities of these COSs were being investigated in different patients, animals and even plants as a broad phase clinical trial program. In the present article, we have discussed the COSs preparation by different methods through comprehensive diffraction procedures along with the merits and demerits given in detail. In addition, a summary of recent work describing the synthesis and biological activities of water-soluble COSs has been presented here.
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spelling um.eprints-107612014-08-20T00:57:43Z http://eprints.um.edu.my/10761/ Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms Ahmed, A.B.A. Taha, R.M. Mohajer, S. Elaagib, M.E. Kim, S.K. QH301 Biology Chitin oligosaccharides (COSs) can be isolated from various natural resources, which have widely been used in biological active supplements (BAS) for the benefit of humankind. Several technological approaches for the preparation of COSs such as enzymatic, chemical, acid-catalysts hydrolysis, microwave radiation, membrane bioreactor methods have been developed and among them, membrane bioreactor, bioconversion and continuous mass production technologies are reported to be excellent. Compounds isolated from natural products have made a drastic impact on the pharmaceutical industry and especially, water-soluble chitin oligosaccharides have shown greater clinical activity, which have been demonstrated in various cell lines of disease significance. The activities of these COSs were being investigated in different patients, animals and even plants as a broad phase clinical trial program. In the present article, we have discussed the COSs preparation by different methods through comprehensive diffraction procedures along with the merits and demerits given in detail. In addition, a summary of recent work describing the synthesis and biological activities of water-soluble COSs has been presented here. 2012 Article PeerReviewed Ahmed, A.B.A. and Taha, R.M. and Mohajer, S. and Elaagib, M.E. and Kim, S.K. (2012) Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms. Russian Journal of Marine Biology, 38 (4). pp. 351-358. ISSN 1063-0740,
spellingShingle QH301 Biology
Ahmed, A.B.A.
Taha, R.M.
Mohajer, S.
Elaagib, M.E.
Kim, S.K.
Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms
title Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms
title_full Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms
title_fullStr Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms
title_full_unstemmed Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms
title_short Preparation, properties and biological applications of water soluble chitin oligosaccharides from marine organisms
title_sort preparation properties and biological applications of water soluble chitin oligosaccharides from marine organisms
topic QH301 Biology
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