Hormonal changes causing rhinitis in pregnancy among Malaysian women

Objectives: To investigate the aetiology of rhinitis occurring in pregnancy, by (1) describing the relationship between pregnancy rhinitis and serum oestrogen, progesterone, placental growth hormone and insulin-like growth factor, and (2) assessing the prevalence of pregnancy rhinitis among Malaysia...

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Main Authors: Indirani, B., Raman, R., Omar, Siti Zawiah
Format: Article
Language:English
Published: Cambridge University Press 2013
Subjects:
Online Access:http://eprints.um.edu.my/10832/1/Indirani-2013-Hormonal_changes_cau.pdf
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author Indirani, B.
Raman, R.
Omar, Siti Zawiah
author_facet Indirani, B.
Raman, R.
Omar, Siti Zawiah
author_sort Indirani, B.
collection UM
description Objectives: To investigate the aetiology of rhinitis occurring in pregnancy, by (1) describing the relationship between pregnancy rhinitis and serum oestrogen, progesterone, placental growth hormone and insulin-like growth factor, and (2) assessing the prevalence of pregnancy rhinitis among Malaysian women. Methods: Prospective study involving 30 pregnant women followed at an ante-natal clinic for 14 months. Hormone levels were analysed during pregnancy and the post-partum period. Results: Levels of all four hormones were elevated in the third trimester, compared with first trimester and postpartum values. Rhinitis patients had higher levels of oestrogen and insulin-like growth factor 1 in the third trimester than non-rhinitis patients, although these differences were not statistically significant. The prevalence of rhinitis was 53.3 per cent, with most cases occurring in the third trimester. Patients with pregnancy rhinitis had a higher prevalence of female babies, compared with non-rhinitis patients (p = 0.003). Conclusions: Pregnancy rhinitis was significantly more common in women giving birth to female babies. Women with pregnancy rhinitis had a non-significant elevation in oestrogen and insulin-like growth factor 1 levels, compared with those without rhinitis.
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spelling um.eprints-108322020-02-20T03:27:04Z http://eprints.um.edu.my/10832/ Hormonal changes causing rhinitis in pregnancy among Malaysian women Indirani, B. Raman, R. Omar, Siti Zawiah R Medicine RG Gynecology and obstetrics Objectives: To investigate the aetiology of rhinitis occurring in pregnancy, by (1) describing the relationship between pregnancy rhinitis and serum oestrogen, progesterone, placental growth hormone and insulin-like growth factor, and (2) assessing the prevalence of pregnancy rhinitis among Malaysian women. Methods: Prospective study involving 30 pregnant women followed at an ante-natal clinic for 14 months. Hormone levels were analysed during pregnancy and the post-partum period. Results: Levels of all four hormones were elevated in the third trimester, compared with first trimester and postpartum values. Rhinitis patients had higher levels of oestrogen and insulin-like growth factor 1 in the third trimester than non-rhinitis patients, although these differences were not statistically significant. The prevalence of rhinitis was 53.3 per cent, with most cases occurring in the third trimester. Patients with pregnancy rhinitis had a higher prevalence of female babies, compared with non-rhinitis patients (p = 0.003). Conclusions: Pregnancy rhinitis was significantly more common in women giving birth to female babies. Women with pregnancy rhinitis had a non-significant elevation in oestrogen and insulin-like growth factor 1 levels, compared with those without rhinitis. Cambridge University Press 2013 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10832/1/Indirani-2013-Hormonal_changes_cau.pdf Indirani, B. and Raman, R. and Omar, Siti Zawiah (2013) Hormonal changes causing rhinitis in pregnancy among Malaysian women. The Journal of Laryngology & Otology, 127 (9). pp. 876-881. ISSN 0022-2151, DOI https://doi.org/10.1017/s0022215113001692 <https://doi.org/10.1017/s0022215113001692>. https://doi.org/10.1017/s0022215113001692 doi:10.1017/s0022215113001692
spellingShingle R Medicine
RG Gynecology and obstetrics
Indirani, B.
Raman, R.
Omar, Siti Zawiah
Hormonal changes causing rhinitis in pregnancy among Malaysian women
title Hormonal changes causing rhinitis in pregnancy among Malaysian women
title_full Hormonal changes causing rhinitis in pregnancy among Malaysian women
title_fullStr Hormonal changes causing rhinitis in pregnancy among Malaysian women
title_full_unstemmed Hormonal changes causing rhinitis in pregnancy among Malaysian women
title_short Hormonal changes causing rhinitis in pregnancy among Malaysian women
title_sort hormonal changes causing rhinitis in pregnancy among malaysian women
topic R Medicine
RG Gynecology and obstetrics
url http://eprints.um.edu.my/10832/1/Indirani-2013-Hormonal_changes_cau.pdf
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AT ramanr hormonalchangescausingrhinitisinpregnancyamongmalaysianwomen
AT omarsitizawiah hormonalchangescausingrhinitisinpregnancyamongmalaysianwomen