Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt

A 16-y-old boy who had undergone bone marrow transplantation for relapsed acute lymphoblastic leukaemia developed liver cirrhosis and refractory ascites, which did not respond to salt restriction, diuretics and abdominal paracentesis. Liver transplantation was not feasible because of poor nutritiona...

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Main Authors: Lee, W.S., McKiernan, P.J., de Goyet, J.D., Tanner, M.S., John, P.R.
Format: Article
Published: 2001
Subjects:
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author Lee, W.S.
McKiernan, P.J.
de Goyet, J.D.
Tanner, M.S.
John, P.R.
author_facet Lee, W.S.
McKiernan, P.J.
de Goyet, J.D.
Tanner, M.S.
John, P.R.
author_sort Lee, W.S.
collection UM
description A 16-y-old boy who had undergone bone marrow transplantation for relapsed acute lymphoblastic leukaemia developed liver cirrhosis and refractory ascites, which did not respond to salt restriction, diuretics and abdominal paracentesis. Liver transplantation was not feasible because of poor nutritional status, pro-existing renal dysfunction and uncertainty about the prognosis of his leukaemia. The patient underwent a Successful transjugular intrahepatic portosystemic shunt (TIPS), with immediate resolution of ascites, enabling cessation of diuretics and improvement in nutritional status. At 24 mo following TIPS there has been no re-accumulation of ascites. Conclusion: TIPS inay have a role in the nianagernent of refractory ascites secondary to liver cirrhosis in selected children.
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spelling um.eprints-109232014-07-14T00:17:30Z http://eprints.um.edu.my/10923/ Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt Lee, W.S. McKiernan, P.J. de Goyet, J.D. Tanner, M.S. John, P.R. R Medicine RJ Pediatrics A 16-y-old boy who had undergone bone marrow transplantation for relapsed acute lymphoblastic leukaemia developed liver cirrhosis and refractory ascites, which did not respond to salt restriction, diuretics and abdominal paracentesis. Liver transplantation was not feasible because of poor nutritional status, pro-existing renal dysfunction and uncertainty about the prognosis of his leukaemia. The patient underwent a Successful transjugular intrahepatic portosystemic shunt (TIPS), with immediate resolution of ascites, enabling cessation of diuretics and improvement in nutritional status. At 24 mo following TIPS there has been no re-accumulation of ascites. Conclusion: TIPS inay have a role in the nianagernent of refractory ascites secondary to liver cirrhosis in selected children. 2001 Article PeerReviewed Lee, W.S. and McKiernan, P.J. and de Goyet, J.D. and Tanner, M.S. and John, P.R. (2001) Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt. Acta Paediatrica, 90 (11). pp. 1352-1355. ISSN 0803-5253, DOI https://doi.org/10.1111/j.1651-2227.2001.tb01590.x <https://doi.org/10.1111/j.1651-2227.2001.tb01590.x>. http://onlinelibrary.wiley.com/doi/10.1111/j.1651-2227.2001.tb01590.x/abstract 10.1111/j.1651-2227.2001.tb01590.x
spellingShingle R Medicine
RJ Pediatrics
Lee, W.S.
McKiernan, P.J.
de Goyet, J.D.
Tanner, M.S.
John, P.R.
Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
title Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
title_full Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
title_fullStr Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
title_full_unstemmed Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
title_short Successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
title_sort successful treatment of refractory ascites in a child with transjugular intrahepatic portosystemic shunt
topic R Medicine
RJ Pediatrics
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